ArticleInfluenza and other respiratory viruses2015
Detection and characterization of respiratory viruses causing acute respiratory illness and asthma exacerbation in children during three different seasons (2011-2014) in Mexico City.
Article in Influenza and other respiratory viruses, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Can we distinguish respiratory viral infections based on clinical features? A prospective pediatric cohort compared to systematic literature review.Reviews in medical virology · 2018Pooled it
- Respiratory virus dynamics in a tropical region: Insights from Yucatán, México (2018-2024).Epidemiology and infection · 2026Article
- Respiratory infections and asthma exacerbations in children: Regional insights into the overlooked role of atypical pathogens in Mexico.The journal of allergy and clinical immunology. Global · 2026Article
- Rhinovirus C15 infection induces airway epithelial cell remodeling and robust inflammatory responses: Potential implications for airway obstruction in children.Mucosal immunology · 2025Article
- Insights from respiratory virus co-infections.World journal of virology · 2024Review
- Frequency of respiratory virus-associated infection among children and adolescents from a tertiary-care hospital in Mexico City.Scientific reports · 2023Article
- Lockdown Fatigue in Pediatric Respiratory Patients: Lessons from the First COVID-19 Year.Children (Basel, Switzerland) · 2022Article
- Asthma in the Americas: An Update: A Joint Perspective from the Brazilian Thoracic Society, Canadian Thoracic Society, Latin American Thoracic Society, and American Thoracic Society.Annals of the American Thoracic Society · 2022Review
- Deficient inflammasome activation permits an exaggerated asthma phenotype in rhinovirus C-infected immature mice.Mucosal immunology · 2021Article
- Rhinovirus C Infection Induces Type 2 Innate Lymphoid Cell Expansion and Eosinophilic Airway Inflammation.Frontiers in immunology · 2021Article
- Influenza virus detection in the stool of children with acute gastroenteritis.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2020Article
- Viral etiology and atopic characteristics in high-risk asthmatic children hospitalized for lower respiratory tract infection.Translational pediatrics · 2020Article
- Advances in laboratory assays for detecting human metapneumovirus.Annals of translational medicine · 2020Review
- Cryo-EM structure of rhinovirus C15a bound to its cadherin-related protein 3 receptor.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Characterization of respiratory infection viruses in hospitalized children from Naples province in Southern Italy.Experimental and therapeutic medicine · 2018Article
- Virome and bacteriome characterization of children with pneumonia and asthma in Mexico City during winter seasons 2014 and 2015.PloS one · 2018Article
- Clinical and virological factors associated with gastrointestinal symptoms in patients with acute respiratory infection: a two-year prospective study in general practice medicine.BMC infectious diseases · 2017Article
- Respiratory viruses detected in Mexican children younger than 5 years old with community-acquired pneumonia: a national multicenter study.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2017Article
- A diagnostic and epidemiologic investigation of acute febrile illness (AFI) in Kilombero, Tanzania.PloS one · 2017Article
- Prevalence of non-influenza respiratory viruses in acute respiratory infection cases in Mexico.PloS one · 2017Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundViral infections play a significant role in causing acute respiratory infections (ARIs) and exacerbations of chronic diseases. Acute respiratory infections are now the leading cause of mortality in children worldwide, especially in developing countries. Recently, human rhinovirus (HRV) infection has been emerged as an important cause of pneumonia and asthma exacerbation.
objectivesTo determine the role of several viral agents principally, respiratory syncytial virus, and HRV in children with ARIs and their relationship with asthma exacerbation and pneumonia.
methodsBetween October 2011 and March 2014, 432 nasopharyngeal samples of children <15 years of age with ARI hospitalized at a referral hospital for respiratory diseases were tested for the presence of respiratory viruses using a multiplex RT-qPCR. Clinical, epidemiological, and demographic data were collected and associated with symptomatology and viral infections.
resultsViral infections were detected in at least 59·7% of the enrolled patients, with HRV (26·6%) being the most frequently detected. HRV infections were associated with clinical features of asthma and difficulty in breathing such as wheezing (P = 0·0003), supraesternal (P = 0·046), and xiphoid retraction (P = 0·030). HRV subtype C (HRV-C) infections were associated with asthma (P = 0·02).
conclusionsHuman rhinovirus was the virus most commonly detected in pediatric patients with ARI. There is also an association of HRV-C infection with asthma exacerbation, emphasizing the relevance of this virus in severe pediatric respiratory disease.
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