Evidence map›Paper›PMID 26289841›Full record

ArticleDevelopmental psychobiology2015

Effects of early adversity on young children's diurnal cortisol rhythms and externalizing behavior.

Kristin Bernard, Jordana Zwerling, Mary Dozier

Abstract read
In one paragraph

Article in Developmental psychobiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kristin BernardDepartment of Psychology, Stony Brook University, Stony Brook, NY, 11794, USA.
Jordana ZwerlingDepartment of Psychology, Stony Brook University, Stony Brook, NY, 11794, USA.
Mary DozierDepartment of Psychology, University of Delaware, Newark, DE, 19716, USA.

Funding

Specialized services for high-risk birth parentsR01MH074374 · NIMH · UNIVERSITY OF DELAWARE · PI DOZIER, MARY, TOTTENHAM, NIM · 2006 to 2023
$10.1M
SPECIALIZED MENTAL HEALTH SERVICES FOR FOSTER INFANTSR01MH052135 · NIMH · UNIVERSITY OF DELAWARE · PI DOZIER, MARY · 1996 to 2014
$6.7M
NIMH NIH HHS R01 MH052135NIMH NIH HHS R01 MH074374
6 · The paper itself

Abstract

Early adversity is associated with biological and behavioral dysregulation in early childhood. We examined whether early adversity (i.e., poverty and involvement with child protective services [CPS]) had an indirect effect on externalizing behavior through HPA axis dysregulation, specifically blunted diurnal cortisol patterns. Participants included 94 children between the ages of 3.94 and 6.52 years old, who had a history of CPS involvement (n = 53) or no history of CPS involvement (n = 41). Cortisol samples were collected at wake-up and bedtime across 3 days, and parent-reported externalizing behavior was assessed using the Child Behavior Checklist. Results showed that history of CPS involvement and poverty were associated with blunted cortisol patterns, which in turn led to elevated externalizing behavior. The indirect effect of CPS involvement on externalizing behavior through blunted cortisol was significant, whereas the indirect effect of poverty on externalizing behavior was nonsignificant. Findings add to our understanding of neurobiological mechanisms linking early adversity to psychopathology.

Indexed as

ChildChild Behavior DisordersChild, PreschoolCircadian RhythmFemaleHumansHydrocortisoneHypothalamo-Hypophyseal SystemMaleModels, TheoreticalPituitary-Adrenal SystemPovertyProblem BehaviorSalivaStress, PsychologicalHydrocortisonecortisolexternalizing behaviormaltreatmentstress

Identifiers

PMID26289841
PMCPMC5773098

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.