ArticleTrials2015
Core Outcomes in Ventilation Trials (COVenT): protocol for a core outcome set using a Delphi survey with a nested randomised trial and observational cohort study.
Article in Trials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 7 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Effectiveness of targeted post-acute interventions and follow-up services for sepsis survivors: a systematic review.Critical care (London, England) · 2025Pooled it
- Feasibility of a RCT of techniques for managing an impacted fetal head during emergency caesarean section: the MIDAS scoping study.Health technology assessment (Winchester, England) · 2023Pooled it
- Patient participation in Delphi surveys to develop core outcome sets: systematic review.BMJ open · 2021Pooled it
- Understanding and Enhancing Sepsis Survivorship. Priorities for Research and Practice.American journal of respiratory and critical care medicine · 2019Pooled it
- Non-invasive ventilation as a strategy for weaning from invasive mechanical ventilation: a systematic review and Bayesian meta-analysis.Intensive care medicine · 2018Pooled it
- Statin therapy for acute respiratory distress syndrome: an individual patient data meta-analysis of randomised clinical trials.Intensive care medicine · 2017Pooled it
- Protocolized versus non-protocolized weaning for reducing the duration of invasive mechanical ventilation in newborn infants.The Cochrane database of systematic reviews · 2016Pooled it
- Family or caregiver outcomes after critical illness (FOCUS): a protocol for a core outcome set development study.BMJ open · 2026Article
- Development of the clinical trial site performance metrics instrument: A study protocol.MethodsX · 2025Article
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- Assessing the safety of physical rehabilitation in critically ill patients: a Delphi study.Critical care (London, England) · 2024Article
- Mechanical ventilation core outcome set uptake in Cochrane systematic reviews: A cross-sectional study.Cochrane evidence synthesis and methods · 2024Article
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- Review
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- Integrating diabetes, hypertension and HIV care in sub-Saharan Africa: a Delphi consensus study on international best practice.BMC health services research · 2021Article
- Article
- Protocol for the development of a core outcome set for evaluating mixed-diagnosis falls prevention interventions for people with Multiple Sclerosis, Parkinson's Disease and stroke.HRB open research · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundAmong clinical trials of interventions that aim to modify time spent on mechanical ventilation for critically ill patients there is considerable inconsistency in chosen outcomes and how they are measured. The Core Outcomes in Ventilation Trials (COVenT) study aims to develop a set of core outcomes for use in future ventilation trials in mechanically ventilated adults and children. METHODS/
designWe will use a mixed methods approach that incorporates a randomised trial nested within a Delphi study and a consensus meeting. Additionally, we will conduct an observational cohort study to evaluate uptake of the core outcome set in published studies at 5 and 10 years following core outcome set publication. The three-round online Delphi study will use a list of outcomes that have been reported previously in a review of ventilation trials. The Delphi panel will include a range of stakeholder groups including patient support groups. The panel will be randomised to one of three feedback methods to assess the impact of the feedback mechanism on subsequent ranking of outcomes. A final consensus meeting will be held with stakeholder representatives to review outcomes. DISCUSSION: The COVenT study aims to develop a core outcome set for ventilation trials in critical care, explore the best Delphi feedback mechanism for achieving consensus and determine if participation increases use of the core outcome set in the long term.
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