SynthesisBMC family practice2015
Systematic review of clinical practice guidelines recommendations about primary cardiovascular disease prevention for older adults.
Synthesis in BMC family practice, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Do we AGREE on the targets of antihypertensive drug treatment in older adults: a systematic review of guidelines on primary prevention of cardiovascular diseases.Age and ageing · 2022Pooled it
- Recommendations for (Discontinuation of) Statin Treatment in Older Adults: Review of Guidelines.Journal of the American Geriatrics Society · 2020Pooled it
- Trust first, concerns second: An international vignette study of older adults' preferences towards deprescribing statins.British journal of clinical pharmacology · 2026Article
- What do clinical practice guidelines say about deprescribing? A scoping review.BMJ quality & safety · 2024Article
- Invited review: Enabling shared decision making in gerontological nursing: Barriers and facilitators.Journal of Korean gerontological nursing · 2024Article
- Assessment of the appropriateness of cardiovascular preventive medication in older people: using the RAND/UCLA Appropriateness Method.BMC geriatrics · 2022Article
- Natriuretic peptide level at heart failure diagnosis and risk of hospitalisation and death in England 2004-2018.Heart (British Cardiac Society) · 2022Article
- Patient Characteristics and General Practitioners' Advice to Stop Statins in Oldest-Old Patients: a Survey Study Across 30 Countries.Journal of general internal medicine · 2019Article
- Hypertension management: experiences, wishes and concerns among older people-a qualitative study.BMJ open · 2019Article
- Article
- Clinical practice guidelines for older people with multimorbidity and life-limiting illness: what are the implications for deprescribing?Therapeutic advances in drug safety · 2018Article
- How general practitioners would deprescribe in frail oldest-old with polypharmacy - the LESS study.BMC family practice · 2018Article
- The importance and challenges of shared decision making in older people with multimorbidity.PLoS medicine · 2018Article
- Prevalence and Variability in Medications Contributing to Polypharmacy in Long-Term Care Facilities.Drugs - real world outcomes · 2017Article
- Primary prevention of cardiovascular disease in older adults in China.World journal of clinical cases · 2017Review
- Application of the 2014 NICE cholesterol guidelines in the English population: a cross-sectional analysis.The British journal of general practice : the journal of the Royal College of General Practitioners · 2017Article
- Hypertension in the Older Adult.Primary care · 2017Review
- General Practitioners' Decision Making about Primary Prevention of Cardiovascular Disease in Older Adults: A Qualitative Study.PloS one · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundClinical care for older adults is complex and represents a growing problem. They are a diverse patient group with varying needs, frequent presence of multiple comorbidities, and are more susceptible to treatment harms. Thus Clinical Practice Guidelines (CPGs) need to carefully consider older adults in order to guide clinicians. We reviewed CPG recommendations for primary cardiovascular disease (CVD) prevention and examined the extent to which CPGs address issues important for older people identified in the literature.
methodsWe searched: 1) two systematic reviews on CPGs for CVD prevention and 2) the National CPG Clearinghouse, G-I-N International CPG Library and Trip databases for CPGs for CVD prevention, hypertension and cholesterol. We conducted our search between April and December 2013. We excluded CPGs for diabetes, chronic kidney disease, HIV, lifestyle, general screening/prevention, and pregnant or pediatric populations. Three authors independently screened citations for inclusion and extracted data. The primary outcomes were presence and extent of recommendations for older people including discussion of: (1) available evidence, (2) barriers to implementation of the CPG, and (3) tailoring management for this group.
resultsWe found 47 eligible CPGs. There was no mention of older people in 4 (9 %) of the CPGs. Benefits were discussed more frequently than harms. Twenty-three CPGs (49 %) discussed evidence about potential benefits and 18 (38 %) discussed potential harms of CVD prevention in older people. Most CPGs addressed one or more barriers to implementation, often as a short statement. Although 27 CPGs (58 %) mentioned tailoring management to the older patient context (e.g. comorbidities), concrete guidance was rare.
conclusionAlthough most CVD prevention CPGs mention the older population to some extent, the information provided is vague and very limited. Older adults represent a growing proportion of the population. Guideline developers must ensure they consider older patients' needs and provide appropriate advice to clinicians in order to support high quality care for this group. CPGs should at a minimum address the available evidence about CVD prevention for older people, and acknowledge the importance of patient involvement.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.