Evidence map›Paper›PMID 26289462›Full record

ArticleJournal of neurophysiology2015

Cadence-dependent changes in corticospinal excitability of the biceps brachii during arm cycling.

Davis A Forman, Devin T G Philpott, Duane C Button, Kevin E Power

Abstract read
In one paragraph

Article in Journal of neurophysiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 45 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Davis A FormanSchool of Human Kinetics and Recreation, Memorial University of Newfoundland, St. John's, Newfoundland, Canada; and.
Devin T G PhilpottSchool of Human Kinetics and Recreation, Memorial University of Newfoundland, St. John's, Newfoundland, Canada; and.
Duane C ButtonSchool of Human Kinetics and Recreation, Memorial University of Newfoundland, St. John's, Newfoundland, Canada; and Faculty of Medicine, Memorial University of Newfoundland, St. John's, Newfoundland, Canada.
Kevin E PowerSchool of Human Kinetics and Recreation, Memorial University of Newfoundland, St. John's, Newfoundland, Canada; and Faculty of Medicine, Memorial University of Newfoundland, St. John's, Newfoundland, Canada kevin.power@mun.ca.
Memorial University of Newfoundland · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This is the first study to report the influence of different cadences on the modulation of supraspinal and spinal excitability during arm cycling. Supraspinal and spinal excitability were assessed using transcranial magnetic stimulation of the motor cortex and transmastoid electrical stimulation of the corticospinal tract, respectively. Transcranial magnetic stimulation-induced motor evoked potentials and transmastoid electrical stimulation-induced cervicomedullary evoked potentials (CMEPs) were recorded from the biceps brachii at two separate positions corresponding to elbow flexion and extension (6 and 12 o'clock relative to a clock face, respectively) while arm cycling at 30, 60 and 90 rpm. Motor evoked potential amplitudes increased significantly as cadence increased during both elbow flexion (P < 0.001) and extension (P = 0.027). CMEP amplitudes also increased with cadence during elbow flexion (P < 0.01); however, the opposite occurred during elbow extension (i.e., decreased CMEP amplitude; P = 0.01). The data indicate an overall increase in the excitability of corticospinal neurons which ultimately project to biceps brachii throughout arm cycling as cadence increased. Conversely, changes in spinal excitability as cadence increased were phase dependent (i.e., increased during elbow flexion and decreased during elbow extension). Phase- and cadence-dependent changes in spinal excitability are suggested to be mediated via changes in the balance of excitatory and inhibitory synaptic input to the motor pool, as opposed to changes in the intrinsic properties of spinal motoneurons.

Indexed as

ArmElbowElectric StimulationElectromyographyEvoked Potentials, MotorHumansMaleMovementMuscle ContractionMuscle, SkeletalPyramidal TractsTranscranial Magnetic StimulationYoung AdultCMEPMEPmotoneurontranscranialtransmastoid

Identifiers

PMID26289462
PMCPMC4609762
OpenAlexW2292493085

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.