Evidence map›Paper›PMID 26289259›Full record

ArticleDigestive diseases and sciences2016

Sense of Coherence and Defense Style Predict Sleep Difficulties in Early Non-metastatic Colorectal Cancer.

Thomas Hyphantis, Panagiota Goulia, Ioannis Zerdes, Solomis Solomou, Elias Andreoulakis, André F Carvalho, Nicholas Pavlidis

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Article in Digestive diseases and sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Factors associated with anxiety in colorectal cancer survivors: a scoping review.Journal of cancer survivorship : research and practice · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Preoperative insomnia and its association with psychological factors, pain and anxiety in Chinese colorectal cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Thomas HyphantisDepartment of Psychiatry, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece. tyfantis@cc.uoi.gr.ORCID http://orcid.org/0000-0002-7647-4312
Panagiota GouliaDepartment of Psychiatry, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece.
Ioannis ZerdesDepartment of Psychiatry, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece.
Solomis SolomouDepartment of Psychiatry, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece.
Elias Andreoulakis3rd Department of Psychiatry, Aristotle University of Thessaloniki, University Campus, Thessaloniki, 54124, Greece.
André F CarvalhoDepartment of Clinical Medicine, Faculty of Medicine, Federal University of Ceará, Fortaleza, CE, Brazil.
Nicholas PavlidisDepartment of Medical Oncology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece.
University of Ioannina · GRAristotle University of Thessaloniki · GRUniversidade Federal do Ceará · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSleep disturbances are common in cancer patients, but little is known about the complex interplay between the background psychological profile, coping with health stressors capacities and psychological distress in the formation of sleep difficulties in colorectal cancer.

aimsTo study the course and to identify psychological predictors of sleep difficulties in early non-metastatic colorectal cancer patients over a one-year period.

methodsIn this 1-year prospective study, we assessed in 84 early non-metastatic colorectal cancer patients the association of psychological distress (SCL-90-R), sense of coherence (SOC-29), and defense styles (Defense Style Questionnaire) with sleep difficulties (SCL-90-R) in multiple regression models. Eighty-two patients with breast cancer and 50 patients with cancer of unknown primary site served as disease controls, and 84 matched for age and sex alleged healthy individuals served as healthy controls.

resultsColorectal cancer patients presented more sleep difficulties compared to healthy participants but fewer than patients with breast cancer and cancer of unknown primary site. Colorectal cancer patients' trouble falling asleep (p = 0.033) and wakening up early in the morning (p < 0.001) deteriorated over time. Sleep that was restless or disturbed was independently associated with low SOC (p = 0.046) and maladaptive defenses (p = 0.008). Anxiety symptoms (p < 0.001) predicted deterioration in trouble falling asleep, while depressive symptoms (p = 0.022) and self-sacrificing defense style (p = 0.049) predicted deterioration in wakening up early in the morning.

conclusionsPsychological parameters and coping with health stressors capacities are independently associated with sleep difficulties in colorectal cancer patients, indicating the need for psychological interventions aiming at improving adjustment to the disease.

Indexed as

Defense MechanismsSense of CoherenceSleepAgedCase-Control StudiesColorectal NeoplasmsFemaleHealth StatusHumansMaleMental HealthMiddle AgedProspective StudiesQuality of LifeRisk AssessmentRisk FactorsColorectal cancerEgo mechanisms of defensePersonalityPsychological distressSense of coherenceSleep

Identifiers

PMID26289259
OpenAlexW1157358071

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.