Understanding antibiotic stewardship for the critically ill.

J J De Waele, J Schouten, G Dimopoulos

Registry-linked trialAbstract read

In one paragraph

Article in Intensive care medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03683693 (Procalcitonin to Guide Antibiotic Stop in Neurocritical Care Patients. An Interventional Matched-cohort Study.), which is not on this map. Cited by 5 papers.

0numbers the graph read from it

0cells of the map it votes in

5citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03683693 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Procalcitonin to Guide Antibiotic Stop in Neurocritical Care Patients. An Interventional Matched-cohort Study.

TypeinterventionalSponsorGeneral Hospital GroeningeRan2018 to 2020Enrolled132ConditionsSepsisArmsProcalcitonin group

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

Impact of a restrictive antibiotic policy on the acquisition of extended-spectrum beta-lactamase-producing Enterobacteriaceae in an endemic region: a before-and-after, propensity-matched cohort study in a Caribbean intensive care unit.Critical care (London, England) · 2021
Observational
What every intensivist must know about antimicrobial stewardship: its pitfalls and its challenges.Revista Brasileira de terapia intensiva · 2020
Article
Impact of pharmacist-led antibiotic stewardship program in a PICU of low/middle-income country.BMJ open quality · 2018
Article
Focus on severe infections.Intensive care medicine · 2017
Review
Abdominal Sepsis.Current infectious disease reports · 2016
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

J J De WaeleDepartment of Critical Care Medicine, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium. jan.dewaele@ugent.be.

J SchoutenDepartment of Intensive Care, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.

G DimopoulosDepartment of Critical Care, University Hospital Attikon Medical School, University of Athens, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Critical IllnessAnti-Bacterial AgentsDrug PrescriptionsHumansInappropriate PrescribingPractice Patterns, Physicians'Anti-Bacterial Agents

Identifiers

PMID26289014

DOI10.1007/s00134-015-4030-8

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

NCT03683693ClinicalTrials.gov

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.