Evidence map›Paper›PMID 26288031›Full record

ArticleAIDS care2015

Repeat pregnancy in women with HIV infection in Latin America and the Caribbean.

Regis Kreitchmann, Karen Megazzini, Victor Hugo Melo, Débora Fernandes Coelho, D Heather Watts, Margot Krauss, Maria Isabel Gouvea, Geraldo Duarte, Marcelo H Losso, George K Siberry

Open access · greenAbstract read
In one paragraph

Article in AIDS care, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 3 countries.

Regis Kreitchmanna Irmandade da Santa Casa de Misericordia de Porto Alegre , Professor Annes Dias 285, Porto Alegre , RS 90020090 , Brazil.
Karen Megazzinib Westat , 1600 Research Blvd, Rockville , MD 20850 , USA.
Victor Hugo Meloc School of Medicine , Federal University of Minas Gerais , Av. Alfredo Balena 190, 2th floor, Belo Horizonte , Brazil.
Débora Fernandes Coelhoa Irmandade da Santa Casa de Misericordia de Porto Alegre , Professor Annes Dias 285, Porto Alegre , RS 90020090 , Brazil.
D Heather Wattsd U.S. Department of State , Washington , DC , USA.
Margot Kraussb Westat , 1600 Research Blvd, Rockville , MD 20850 , USA.
Maria Isabel Gouveae Hospital Federal dos Servidores do Estado , Rua Sacadura Cabral, 178, Anexo IV, 4 andar, Rio de Janeiro , RJ - CEP 20221903 , Brazil.
Geraldo Duartef Faculty of Medicine of Ribeirão Preto , University of São Paulo , Avenida Bandeirantes 3900, Ribeirão Preto, São Paulo , Brazil.
Marcelo H Lossog HIV Unit , Hospital General de Agudos Jose Maria Ramos Mejia , Urquiza 609, Pabellon de Clinicas, 2 Piso, C1221ADC Buenos Aires , Argentina.
George K Siberryh Maternal Pediatric Infectious Disease (MPID) Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) , National Institutes of Health , 6100 Executive Blvd., Room 4B11H, Bethesda , MD 20892-7510 , USA.
Irmandade da Santa Casa de Misericórdia de São Paulo · BRWestat (United States) · USEunice Kennedy Shriver National Institute of Child Health and Human Development · USHospital Federal dos Servidores do Estado · BRHospital Ramos Mejía · ARUnited States Department of State · USUniversidade de São Paulo · BRUniversidade Federal de Minas Gerais · BR

Funding

NICHD INTERNATIONAL PEDIATRIC AND PERINATAL HIV STUDIES NETWORK COORDI-275033345N01HD033345 · NICHD · WESTAT · PI NESEL, CAROL · 2004 to 2006
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NICHD NIH HHS HHSN267200800001CNICHD NIH HHS HHSN275201300003CNICHD NIH HHS N01-HD-3-3345NIDDK NIH HHS HHSN267200800001G
6 · The paper itself

Abstract

Intended and unintended pregnancies occur frequently among human immunodeficiency virus (HIV)-infected women. We evaluated the occurrence of repeat pregnancy and characteristics associated with this outcome among HIV-infected women in Latin America and the Caribbean who were participating in the National Institute of Child Health and Human Development (NICHD) International Site Development Initiative (NISDI). Of the 1342 HIV-infected pregnant women enrolled in NISDI, 124 (9.2%) had one or more repeat pregnancies on study. Median time between the index delivery and date of conception of the subsequent pregnancy was 1.4 years (range 0.1-5.7). Younger age (odds ratio [OR] = 1.07, 95% confidence interval [CI]: 1.04-1.11 per one year decrease in age), hospitalization during the index pregnancy or up to six months post-partum [OR = 2.0, 95% CI: 1.2-3.4], and poor index pregnancy outcome (stillbirth or spontaneous/therapeutic abortion; OR = 3.4, 95% CI: 1.4-8.4) were associated with increased occurrence of repeat pregnancy in multivariable analysis. Among women with repeat pregnancies, the proportion receiving antiretroviral treatment (vs. prophylaxis) increased from 39.4% at the time of the index pregnancy to 81.8% at the time of the repeat pregnancy (p < 0.001). These results can help identify women most likely to benefit from reproductive counseling in order to assist with healthy pregnancy planning and prevention of unintended pregnancies.

Indexed as

Pregnancy, UnplannedAdolescentAdultCaribbean RegionFamily Planning ServicesFemaleHIV InfectionsHumansInfectious Disease Transmission, VerticalLatin AmericaPregnancyPregnancy Complications, InfectiousPregnancy OutcomeYoung AdultHIVLatin Americapredictors of repeat pregnancypregnancy

Identifiers

PMID26288031
PMCPMC4929011
OpenAlexW2154629722

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.