ArticlePloS one2015
Transcatheter Arterial Embolization Alone for Giant Hepatic Hemangioma.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
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Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- Percutaneous Sclerotherapy Versus Transarterial Chemoembolization for Giant Hepatic Hemangiomas: A Systematic Review and Meta-analysis.Cardiovascular and interventional radiology · 2025Pooled it
- Effectiveness of Transarterial Embolization in Treatment of Symptomatic Hepatic Hemangiomas: Systematic Review and Meta-analysis.Cardiovascular and interventional radiology · 2021Pooled it
- Laparoscopic right hepatectomy for giant hepatic hemangioma with endoscopic nasobiliary drainage-guided biliary confirmation.Annals of hepato-biliary-pancreatic surgery · 2026Article
- Successful long-term results (> 5 years) of superselective transarterial chemoembolization in symptomatic/enlarging liver hemangiomas: a paradigm shift at a hepatopancreatobiliary surgery unit.Frontiers in medicine · 2026Article
- Endovascular treatment of giant hepatic hemangiomas: a systematic review and meta-analysis.Jornal vascular brasileiro · 2025Review
- Transarterial chemoembolization with bleomycin and lipiodol: a novel treatment for giant hepatic haemangiomas.Polish journal of radiology · 2025Article
- Diagnosis of liver hemangioma using magnetic resonance diffusion-derived vessel density (DDVD) pixelwise map: a preliminary descriptive study.Quantitative imaging in medicine and surgery · 2024Article
- Long-Term Outcomes of Transarterial Chemoembolization of Giant Liver Hemangiomas with Lipiodol-Bleomycin Emulsion.Cardiovascular and interventional radiology · 2024Article
- Transarterial embolization with bleomycin-lipiodol emulsion: a successful minimal invasive approach for giant liver hemangioma.Clinical journal of gastroenterology · 2024Article
- Hepatic Hemangioma: Review of Imaging and Therapeutic Strategies.Medicina (Kaunas, Lithuania) · 2024Review
- Article
- Safety and Feasibility of Transarterial Bleomycin-Lipiodol Embolization in Patients with Giant Hepatic Hemangiomas.Medicina (Kaunas, Lithuania) · 2023Article
- Case Report: The value of contrast-enhanced ultrasound and contrast-enhanced computed tomography in the diagnosis of hepatic angiosarcoma.Frontiers in oncology · 2023Article
- Transarterial embolization for rare spontaneous subacute intratumoral hemorrhage of hepatic hemangioma: a case report and literature review.Translational cancer research · 2022Article
- The surgical outcomes and risk factors of giant hepatic haemangiomas: a single centre experience.BMC surgery · 2022Article
- Interventional treatments for hepatic hemangioma: A state-of-the-art review.Journal of interventional medicine · 2022Article
- Giant hepatic hemangioma treatment with transcatheter arterial embolisation and transcatheter arterial chemoembolisation; Comparative resultsTurkish journal of medical sciences · 2021Article
- Real-world data on the clinicopathological traits and outcomes of hospitalized liver hemangioma patients: a multicenter study.Annals of translational medicine · 2021Article
- Article
- Endovascular approaches in pediatric interventional oncology.CVIR endovascular · 2021Review
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Giant hepatic hemangioma is a benign liver condition that may be treated using surgery. We studied the digital subtraction angiographic (DSA) characteristics of giant hepatic hemangioma, and the effectiveness of transcatheter arterial embolization (TAE) alone for its treatment. This was a retrospective study of 27 patients diagnosed with giant hepatic hemangioma and treated with TAE alone (using lipiodol mixed with pingyangmycin) at the Division of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University, between January 2010 and March 2013. The feeding arteries were identified using DSA. All patients were followed up for between three weeks and 12 months. Changes in tumor diameter and symptoms were observed. The 27 patients included had giant hepatic hemangiomas ranging from 5.3 to 24.5 cm (mean, 11.24±5.08 cm) in the right (n = 13), left (n = 1) or both (n = 13) lobes. Preoperative hepatic angiography showed multiple abnormal vascular lakes in the early phase, known as the "early leaving but late returning, hanging nut on a twig" sign. On the day after TAE, hepatic transaminase levels were increased (ALT: 22.69±17.95 to 94.88±210.32 U/L; ALT: 24.00±12.37 to 99.70±211.54 U/L; both P<0.05), but not total bilirubin. Six patients complained of abdominal pain, and 12 experienced transient fever. In the months after TAE, tumor size decreased (baseline: 11.24±5.08; 3 months: 8.95±4.33; 6 months: 7.60±3.90 cm; P<0.05), and the patients' condition improved. These results indicated that TAE was effective and safe for treating giant hepatic hemangioma. TAE may be a useful alternative to surgery for the treatment of hepatic hemangioma.
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