ReviewResearch synthesis methods2015
Get real in individual participant data (IPD) meta-analysis: a review of the methodology.
Review in Research synthesis methods, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 160 papers, 54 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
160 citing papers in PubMed, 54 syntheses or guidelines pooled it.
- Evaluating Reduced Use and Abstinence as Outcomes in Pharmacotherapy Trials for Stimulant Use Disorder: A Meta-Analysis of 12 Randomized Controlled Trials.JAMA psychiatry · 2026Pooled it
- The risk for the development of hypertensive complications in oocyte donation pregnancy: a systematic review and individual participant data meta-analysis (DONOR IPD).Human reproduction update · 2026Pooled it
- Gender differences in the impact of psychological distress on methamphetamine use disorder outcomes and treatment effect.Addiction (Abingdon, England) · 2026Pooled it
- Which immigrants do citizens prefer? A meta-reanalysis of 100 conjoint experiments.Science advances · 2026Pooled it
- Deep Brain Stimulation for Post-Stroke Movement Disorders of Various Etiologies: An Individual Participant Data (IPD) Meta-Analysis.Brain and behavior · 2026Pooled it
- Exercise dose and modality for blood pressure reduction in predominantly postmenopausal women: a dose-response network meta-analysis.Frontiers in medicine · 2026Pooled it
- Effects of high-intensity interval training and moderate-intensity continuous training on type 2 diabetes mellitus: a meta-analysis and systematic review.Frontiers in endocrinology · 2026Pooled it
- Thyroid antibody status, thyroid function, and the risk of coronary heart disease and stroke: an individual participant data analysis from 14 cohorts.European journal of endocrinology · 2025Pooled it
- Prognostic accuracy of clinical markers of postpartum bleeding in predicting maternal mortality or severe morbidity: a WHO individual participant data meta-analysis.Lancet (London, England) · 2025Pooled it
- P2YBMJ (Clinical research ed.) · 2025Pooled it
- Fasting Before Cardiac Catheterization: Still Necessary? A Systematic Review and Meta-Analysis of Randomized Clinical Trials.Journal of the American Heart Association · 2025Pooled it
- Diabetes and the risk of cardiovascular events and all-cause mortality among older adults: an individual participant data analysis of five prospective studies.European journal of clinical investigation · 2025Pooled it
- Susceptibility to online misinformation: A systematic meta-analysis of demographic and psychological factors.Proceedings of the National Academy of Sciences of the United States of America · 2024Pooled it
- Tranexamic acid for postpartum bleeding: a systematic review and individual patient data meta-analysis of randomised controlled trials.Lancet (London, England) · 2024Pooled it
- Moderators of exercise effects on self-reported cognitive functioning in cancer survivors: an individual participant data meta-analysis.Journal of cancer survivorship : research and practice · 2024Pooled it
- Pooled it
- Endometrial scratching in women undergoing IVF/ICSI: an individual participant data meta-analysis.Human reproduction update · 2023Pooled it
- Two-stage or not two-stage? That is the question for IPD meta-analysis projects.Research synthesis methods · 2023Pooled it
- An individual patient data meta-analysis to determine cut-offs for and confounders of NAFLD-fibrosis staging with magnetic resonance elastography.Journal of hepatology · 2023Pooled it
- An Introduction to Individual Participant Data Meta-analysis.Neurology · 2023Pooled it
100 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Individual participant data (IPD) meta-analysis is an increasingly used approach for synthesizing and investigating treatment effect estimates. Over the past few years, numerous methods for conducting an IPD meta-analysis (IPD-MA) have been proposed, often making different assumptions and modeling choices while addressing a similar research question. We conducted a literature review to provide an overview of methods for performing an IPD-MA using evidence from clinical trials or non-randomized studies when investigating treatment efficacy. With this review, we aim to assist researchers in choosing the appropriate methods and provide recommendations on their implementation when planning and conducting an IPD-MA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.