Evidence map›Paper›PMID 26287679›Full record

ArticleImmunity2015

ILC Lineage Specification: To Be or Not 11b, That Is the Question.

Tomasz Kostrzewski, Hugh J M Brady

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Immunity, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Switch hitter: Bcl11b in T cells and ILC2s.The Journal of experimental medicine · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Tomasz KostrzewskiDepartment of Life Sciences, Imperial College, London SW7 2AZ, UK.
Hugh J M BradyDepartment of Life Sciences, Imperial College, London SW7 2AZ, UK. Electronic address: h.brady@imperial.ac.uk.
Imperial College London · GB

Funding

Medical Research Council G0901737
6 · The paper itself

Abstract

The transcription factor Bcl11b is important for T cell development and maintaining their phenotype. In this issue of Immunity, Califano et al. (2015) show that Bcl11b has a role in specifying type II innate lymphoid cell (ILC2) identity and blocks their conversion to ILC3s.

Indexed as

AnimalsCitrobacter rodentiumEnterobacteriaceae InfectionsEosinophilsLymphocytesLymphocyte SubsetsNeutrophilsRepressor ProteinsTh2 CellsTumor Suppressor ProteinsRepressor ProteinsTumor Suppressor Proteins

Identifiers

PMID26287679
OpenAlexW1885463038

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.