Evidence map›Paper›PMID 26287524›Full record

ArticleeLife2015

Stressing about misplaced fat is a key to longevity.

George A Lemieux, Kaveh Ashrafi

Abstract readComment
In one paragraph

Article in eLife, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Deciphering Differential Life Stage Radioinduced Reproductive Decline inInternational journal of molecular sciences · 2021
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

George A LemieuxDepartment of Physiology, University of California, San Francisco, United States.
Kaveh AshrafiDepartment of Physiology, University of California, San Francisco, United States.

Funding

Research BaseP30DK063720 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KRUMMEL, MATTHEW F · 2003 to 2019
$21.8M
UCSF Nutrition Obesity Research CenterP30DK098722 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTIAN VAISSE · 2015 to 2026
$14.6M
Linking metabolism, neural function, and agingR01AG046400 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ASHRAFI, KAVEH · 2014 to 2023
$4.3M
NIA NIH HHS R01 AG046400NIDDK NIH HHS P30 DK063720NIDDK NIH HHS P30 DK098722
6 · The paper itself

Abstract

The abnormal accumulation of fat increases the lifespans of nematodes that lack sex cells.

Indexed as

Gene Expression RegulationLipid MetabolismAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsDNA-Binding ProteinsGerm CellsTranscription FactorsCaenorhabditis elegans ProteinsDNA-Binding ProteinsTranscription FactorsagingC. eleganscell biologychromosomesfatty acid signalinggenesgermline stem cellslipid metabolismproteostasisSKN-1/Nrf

Identifiers

PMID26287524
PMCPMC4541491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.