Evidence map›Paper›PMID 26287254›Full record

ReviewBiosensors2015

Point-of-Care Diagnostics in Low Resource Settings: Present Status and Future Role of Microfluidics.

Shikha Sharma, Julia Zapatero-Rodríguez, Pedro Estrela, Richard O'Kennedy

Abstract readReview
In one paragraph

Review in Biosensors, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
124citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

124 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  4. Peroxidase-Mimicking Nanozymes for Rapid Detection of Infectious Diseases.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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64 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shikha SharmaBiomedical Diagnostics Institute (BDI), Dublin City University, Glasnevin, Dublin 9, Ireland. shikha.sharma@dcu.ie.
Julia Zapatero-RodríguezBiomedical Diagnostics Institute (BDI), Dublin City University, Glasnevin, Dublin 9, Ireland. julia.zapatero@dcu.ie.
Pedro EstrelaDepartment of Electronic and Electrical Engineering, University of Bath, Bath BA2 7AY, UK. P.Estrela@bath.ac.uk.
Richard O'KennedyBiomedical Diagnostics Institute (BDI), Dublin City University, Glasnevin, Dublin 9, Ireland. richard.okennedy@dcu.ie.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The inability to diagnose numerous diseases rapidly is a significant cause of the disparity of deaths resulting from both communicable and non-communicable diseases in the developing world in comparison to the developed world. Existing diagnostic instrumentation usually requires sophisticated infrastructure, stable electrical power, expensive reagents, long assay times, and highly trained personnel which is not often available in limited resource settings. This review will critically survey and analyse the current lateral flow-based point-of-care (POC) technologies, which have made a major impact on diagnostic testing in developing countries over the last 50 years. The future of POC technologies including the applications of microfluidics, which allows miniaturisation and integration of complex functions that facilitate their usage in limited resource settings, is discussed The advantages offered by such systems, including low cost, ruggedness and the capacity to generate accurate and reliable results rapidly, are well suited to the clinical and social settings of the developing world.

Indexed as

Developing CountriesHealth ResourcesPoint-of-Care SystemsBiosensing TechniquesHumansImmunoassayMicrofluidicsglobal healthlateral flow immunoassaylow-cost biosensorsmicrofluidicspoint-of-care diagnostics

Identifiers

PMID26287254
PMCPMC4600173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.