Evidence map›Paper›PMID 26287196›Full record

ArticleSensors (Basel, Switzerland)2015

Quadruplex Integrated DNA (QuID) Nanosensors for Monitoring Dopamine.

Jennifer M Morales, Christopher G Skipwith, Heather A Clark

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Imaging in vivo acetylcholine release in the peripheral nervous system with a fluorescent nanosensor.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  2. Review
  3. Recent Developments in Nanosensors for Imaging Applications in Biological Systems.Annual review of analytical chemistry (Palo Alto, Calif.) · 2019
    Review
  4. Optical Probes for Neurobiological Sensing and Imaging.Accounts of chemical research · 2018
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jennifer M MoralesDepartment of Pharmaceutical Sciences, Northeastern University, 206 The Fenway, 360 Huntington Avenue, Boston, MA 02115, USA. morales.je@husky.neu.edu.
Christopher G SkipwithDepartment of Pharmaceutical Sciences, Northeastern University, 206 The Fenway, 360 Huntington Avenue, Boston, MA 02115, USA. c.skipwith@neu.edu.
Heather A ClarkDepartment of Pharmaceutical Sciences, Northeastern University, 206 The Fenway, 360 Huntington Avenue, Boston, MA 02115, USA. h.clark@neu.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dopamine is widely innervated throughout the brain and critical for many cognitive and motor functions. Imbalances or loss in dopamine transmission underlie various psychiatric disorders and degenerative diseases. Research involving cellular studies and disease states would benefit from a tool for measuring dopamine transmission. Here we show a Quadruplex Integrated DNA (QuID) nanosensor platform for selective and dynamic detection of dopamine. This nanosensor exploits DNA technology and enzyme recognition systems to optically image dopamine levels. The DNA quadruplex architecture is designed to be compatible in physically constrained environments (110 nm) with high flexibility, homogeneity, and a lower detection limit of 110 µM.

Indexed as

G-QuadruplexesAgaricalesBiosensing TechniquesDopamineMonophenol MonooxygenaseNanoparticlesNegative StainingPorphyrinsSpectrum AnalysisDopamineMonophenol MonooxygenaseporphinePorphyrinsdendrimerDNAdopamineenzymenanosensortyrosinase

Identifiers

PMID26287196
PMCPMC4570402

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.