Evidence map›Paper›PMID 26287177›Full record

ReviewInternational journal of molecular sciences2015

Disease Resistance Gene Analogs (RGAs) in Plants.

Manoj Kumar Sekhwal, Pingchuan Li, Irene Lam, Xiue Wang, Sylvie Cloutier, Frank M You

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 140 papers.

0numbers the graph read from it
0cells of the map it votes in
140citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

140 citing papers in PubMed.

  1. Article
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  9. Molecular Breeding for Fungal Resistance in Common Bean.International journal of molecular sciences · 2025
    Review
  10. Article
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  13. Chromosome-level genome assembly of Pontederia cordata L. provides insights into its rapid adaptation and variation of flower colours.DNA research : an international journal for rapid publication of reports on genes and genomes · 2025
    Article
  14. Article
  15. Article
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80 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Manoj Kumar SekhwalCereal Research Centre, Agriculture and Agri-Food Canada, Morden, MB R6M 1Y5, Canada. manoj.sekhwal@agr.gc.ca.
Pingchuan LiCereal Research Centre, Agriculture and Agri-Food Canada, Morden, MB R6M 1Y5, Canada. pingchuan.li@agr.gc.ca.
Irene LamCereal Research Centre, Agriculture and Agri-Food Canada, Morden, MB R6M 1Y5, Canada. irene.lam@agr.gc.ca.
Xiue WangNational Key Laboratory of Crop Genetics and Germplasm Enhancement, Cytogenetics Institute, Nanjing Agricultural University, Nanjing 210095, China. xiuew@njau.edu.cn.
Sylvie CloutierEastern Cereal and Oilseed Research Centre, Agriculture and Agri-Food Canada, Ottawa, ON K1A 0C6, Canada. sylvie.j.cloutier@agr.gc.ca.
Frank M YouCereal Research Centre, Agriculture and Agri-Food Canada, Morden, MB R6M 1Y5, Canada. frank.you@agr.gc.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plants have developed effective mechanisms to recognize and respond to infections caused by pathogens. Plant resistance gene analogs (RGAs), as resistance (R) gene candidates, have conserved domains and motifs that play specific roles in pathogens' resistance. Well-known RGAs are nucleotide binding site leucine rich repeats, receptor like kinases, and receptor like proteins. Others include pentatricopeptide repeats and apoplastic peroxidases. RGAs can be detected using bioinformatics tools based on their conserved structural features. Thousands of RGAs have been identified from sequenced plant genomes. High-density genome-wide RGA genetic maps are useful for designing diagnostic markers and identifying quantitative trait loci (QTL) or markers associated with plant disease resistance. This review focuses on recent advances in structures and mechanisms of RGAs, and their identification from sequenced genomes using bioinformatics tools. Applications in enhancing fine mapping and cloning of plant disease resistance genes are also discussed.

Indexed as

Genes, PlantDisease ResistanceGenome, PlantPlant DiseasesPlantsQuantitative Trait Locidisease resistance genegene miningnucleotide binding site leucine rich repeat (NBS-LRR)pentatricopeptide repeats (PPRs)receptor like kinase (RLK)receptor like protein (RLP)resistance gene analog (RGA)small RNA (sRNA)

Identifiers

PMID26287177
PMCPMC4581296

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.