ArticleProceedings of the National Academy of Sciences of the United States of America2015
Genome expansion via lineage splitting and genome reduction in the cicada endosymbiont Hodgkinia.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed.
- First Record ofInsects · 2026Article
- Genome degradation results in nested symbiosis and endosymbiont replacement in cicadas.Nature communications · 2025Article
- From eggs to guts: Symbiotic association of Sodalis nezarae sp. nov. with the Southern green shield bug Nezara viridula.FEMS microbiology ecology · 2025Article
- Whole Genome Sequences ofCurrent genomics · 2025Article
- Unveiling detoxifying symbiosis and dietary influence on the Southern green shield bug microbiota.FEMS microbiology ecology · 2024Article
- Article
- Segregation of endosymbionts in complex symbiotic system of cicadas providing novel insights into microbial symbioses and evolutionary dynamics of symbiotic organs in sap-feeding insects.Frontiers in zoology · 2024Article
- Limited variation in microbial communities across populations of Macrosteles leafhoppers (Hemiptera: Cicadellidae).Environmental microbiology reports · 2024Article
- Retention of an Endosymbiont for the Production of a Single Molecule.Genome biology and evolution · 2024Article
- Highly Reduced Complementary Genomes of Dual Bacterial Symbionts in the Mulberry Psyllid Anomoneura mori.Microbes and environments · 2024Article
- Symbionts inApplied and environmental microbiology · 2023Article
- No Transcriptional Compensation for Extreme Gene Dosage Imbalance in Fragmented Bacterial Endosymbionts of Cicadas.Genome biology and evolution · 2023Article
- Cheating leads to the evolution of multipartite viruses.PLoS biology · 2023Article
- A Study on Symbiotic Systems of Cicadas Provides New Insights into Distribution of Microbial Symbionts and Improves Fluorescence In Situ Hybridization Technique.International journal of molecular sciences · 2023Article
- Microbiome and plant cell transformation trigger insect gall induction in cassava.Frontiers in plant science · 2023Article
- Lack of host phylogenetic structure in the gut bacterial communities of New Zealand cicadas and their interspecific hybrids.Scientific reports · 2022Article
- Gut microbiome insights from 16S rRNA analysis of 17-year periodical cicadas (Hemiptera: Magicicada spp.) Broods II, VI, and X.Scientific reports · 2022Article
- Rational engineering of a synthetic insect-bacterial mutualism.Current biology : CB · 2022Article
- A complex interplay of evolutionary forces continues to shape ancient co-occurring symbiont genomes.iScience · 2022Article
- Human follicular mites: Ectoparasites becoming symbionts.Molecular biology and evolution · 2022Article
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6 authors.
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Abstract
Comparative genomics from mitochondria, plastids, and mutualistic endosymbiotic bacteria has shown that the stable establishment of a bacterium in a host cell results in genome reduction. Although many highly reduced genomes from endosymbiotic bacteria are stable in gene content and genome structure, organelle genomes are sometimes characterized by dramatic structural diversity. Previous results from Candidatus Hodgkinia cicadicola, an endosymbiont of cicadas, revealed that some lineages of this bacterium had split into two new cytologically distinct yet genetically interdependent species. It was hypothesized that the long life cycle of cicadas in part enabled this unusual lineage-splitting event. Here we test this hypothesis by investigating the structure of the Ca. Hodgkinia genome in one of the longest-lived cicadas, Magicicada tredecim. We show that the Ca. Hodgkinia genome from M. tredecim has fragmented into multiple new chromosomes or genomes, with at least some remaining partitioned into discrete cells. We also show that this lineage-splitting process has resulted in a complex of Ca. Hodgkinia genomes that are 1.1-Mb pairs in length when considered together, an almost 10-fold increase in size from the hypothetical single-genome ancestor. These results parallel some examples of genome fragmentation and expansion in organelles, although the mechanisms that give rise to these extreme genome instabilities are likely different.
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