ArticleCerebral cortex (New York, N.Y. : 1991)2015
Psychotic Experiences, Working Memory, and the Developing Brain: A Multimodal Neuroimaging Study.
Article in Cerebral cortex (New York, N.Y. : 1991), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Incidence and Persistence of Psychotic Experiences in the General Population: Systematic Review and Meta-Analysis.Schizophrenia bulletin · 2023Pooled it
- Enhancing task fMRI individual difference research with neural signatures.medRxiv : the preprint server for health sciences · 2025Article
- The impact of cumulative obstetric complications and childhood trauma on brain volume in young people with psychotic experiences.Molecular psychiatry · 2023Article
- Persistent and distressing psychotic-like experiences using adolescent brain cognitive development℠ study data.Molecular psychiatry · 2022Article
- The impact of genetic risk for Alzheimer's disease on the structural brain networks of young adults.Frontiers in neuroscience · 2022Article
- Predicting persistence of hallucinations from childhood to adolescence.The British journal of psychiatry : the journal of mental science · 2021Article
- Task-related neural mechanisms of persecutory ideation in schizophrenia and community monozygotic twin-pairs.Human brain mapping · 2021Article
- Increased functional interaction within frontoparietal network during working memory task in major depressive disorder.Human brain mapping · 2021Article
- Complement pathway changes at age 12 are associated with psychotic experiences at age 18 in a longitudinal population-based study: evidence for a role of stress.Molecular psychiatry · 2021Article
- Early Interventions for Clinical High-Risk State for Psychosis.Noro psikiyatri arsivi · 2021Review
- Association of preceding psychosis risk states and non-psychotic mental disorders with incidence of clinical psychosis in the general population: a prospective study in the NEMESIS-2 cohort.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2020Article
- Psychotic-like experiences, polygenic risk scores for schizophrenia, and structural properties of the salience, default mode, and central-executive networks in healthy participants from UK Biobank.Translational psychiatry · 2020Article
- Binge drinking during pregnancy and psychosis-like experiences in the child at age 11.European child & adolescent psychiatry · 2020Article
- Population neuroimaging: generation of a comprehensive data resource within the ALSPAC pregnancy and birth cohort.Wellcome open research · 2020Article
- Reduced parietofrontal effective connectivity during a working-memory task in people with high delusional ideationJournal of psychiatry & neuroscience : JPN · 2019Article
- Blood-Based Protein Changes in Childhood Are Associated With Increased Risk for Later Psychotic Disorder: Evidence From a Nested Case-Control Study of the ALSPAC Longitudinal Birth Cohort.Schizophrenia bulletin · 2018Article
- Commentary: Deficient approaches to human neuroimaging.Frontiers in human neuroscience · 2017Article
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Authors and funding
10 authors.
Funding
Abstract
Psychotic experiences (PEs) occur in the general population, especially in children and adolescents, and are associated with poor psychosocial outcomes, impaired cognition, and increased risk of transition to psychosis. It is unknown how the presence and persistence of PEs during early adulthood affects cognition and brain function. The current study assessed working memory as well as brain function and structure in 149 individuals, with and without PEs, drawn from a population cohort. Observer-rated PEs were classified as persistent or transient on the basis of longitudinal assessments. Working memory was assessed using the n-back task during fMRI. Dynamic causal modeling (DCM) was used to characterize frontoparietal network configuration and voxel-based morphometry was utilized to examine gray matter. Those with persistent, but not transient, PEs performed worse on the n-back task, compared with controls, yet showed no significant differences in regional brain activation or brain structure. DCM analyses revealed greater emphasis on frontal connectivity within a frontoparietal network in those with PEs compared with controls. We propose that these findings portray an altered configuration of working memory function in the brain, potentially indicative of an adaptive response to atypical development associated with the manifestation of PEs.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.