Evidence map›Paper›PMID 26286858›Full record

ArticleMammalian genome : official journal of the International Mammalian Genome Society2015

Collaborative Cross and Diversity Outbred data resources in the Mouse Phenome Database.

Molly A Bogue, Gary A Churchill, Elissa J Chesler

Abstract read
In one paragraph

Article in Mammalian genome : official journal of the International Mammalian Genome Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Fifteen years of the Diversity Outbred mouse model: a review.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
    Review
  5. Article
  6. Article
  7. The Biology ofAnnual review of microbiology · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Single-Cell Transcriptomics of Bone Marrow Stromal Cells in Diversity Outbred Mice: A Model for Population-Level scRNA-Seq Studies.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2023
    Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Molly A BogueThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME, 04609, USA. molly.bogue@jax.org.
Gary A ChurchillThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME, 04609, USA.
Elissa J CheslerThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME, 04609, USA.

Funding

Shared Resource ManagementP30CA034196 · NCI · JACKSON LABORATORY · PI William Carl Skarnes · 1985 to 2026
$61.9M
UNC and PERLEGEN, IncP50GM076468 · NIGMS · JACKSON LABORATORY · PI PETKOV, PETKO M · 2006 to 2015
$31.0M
Translational CoreP30AG038070 · NIA · JACKSON LABORATORY · PI John Matthew Mahoney · 2010 to 2026
$19.3M
Mouse Phenome ProjectR01DA028420 · NIDA · JACKSON LABORATORY · PI Elissa J Chesler · 2010 to 2026
$9.5M
Discovery of Addiction-Related Genes with Advanced Mouse ResourcesR01DA037927 · NIDA · JACKSON LABORATORY · PI CHESLER, ELISSA J · 2015 to 2025
$8.1M
NCI NIH HHS P30 CA034196NIA NIH HHS NIH AG038070NIA NIH HHS P30 AG038070NIDA NIH HHS NIH DA028420NIDA NIH HHS NIH DA037927NIDA NIH HHS R01 DA028420NIDA NIH HHS R01 DA037927NIGMS NIH HHS NIH GM076468NIGMS NIH HHS P50 GM076468
6 · The paper itself

Abstract

The Mouse Phenome Database was originally conceived as a platform for the integration of phenotype data collected on a defined collection of 40 inbred mouse strains--the "phenome panel." This model provided an impetus for community data sharing, and integration was readily achieved through the reproducible genotypes of the phenome panel strains. Advances in the development of mouse populations lead to an expanded role of the Mouse Phenome Database to encompass new strain panels and inbred strain crosses. The recent introduction of the Collaborative Cross and Diversity Outbred mice, which share an extensive pool of genetic variation from eight founder inbred strains, presents new opportunities and challenges for community data resources. A wide variety of molecular and clinical phenotypes are being collected across genotypes, tissues, ages, environmental exposures, interventions, and treatments. The Mouse Phenome Database provides a framework for retrieval, integration, analysis, and display of these data, enabling them to be evaluated in the context of existing data from standard inbred strains. Primary data in the Mouse Phenome Database are supported by extensive metadata on protocols and procedures. These are centrally curated to ensure accuracy and reproducibility and to provide data in consistent formats. The Mouse Phenome Database represents an established and growing community data resource for mouse phenotype data and encourages submissions from new mouse resources, enabling investigators to integrate existing data into their studies of the phenotypic consequences of genetic variation.

Indexed as

Genetic VariationGenotypePhenotypeAnimalsDatabases, GeneticMiceMice, Inbred Strains

Identifiers

PMID26286858
PMCPMC4602074

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.