Evidence map›Paper›PMID 26286810›Full record

ArticleBioinformatics (Oxford, England)2015

GenomeLaser: fast and accurate haplotyping from pedigree genotypes.

Wenzhi Li, Guoxing Fu, Weinian Rao, Wei Xu, Li Ma, Shiwen Guo, Qing Song

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. References for Haplotype Imputation in the Big Data Era.Molecular biology (Los Angeles, Calif.) · 2015
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wenzhi LiDepartment of Neurosurgery, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061 China, Cardiovascular Research Institute and Department of Medicine, Morehouse School of Medicine, Atlanta, GA, 30310 USA.
Guoxing Fu4DGENOME Inc, Atlanta, GA, 30033 USA and.
Weinian Rao4DGENOME Inc, Atlanta, GA, 30033 USA and.
Wei XuCardiovascular Research Institute and Department of Medicine, Morehouse School of Medicine, Atlanta, GA, 30310 USA.
Li MaCardiovascular Research Institute and Department of Medicine, Morehouse School of Medicine, Atlanta, GA, 30310 USA, 4DGENOME Inc, Atlanta, GA, 30033 USA and.
Shiwen GuoDepartment of Neurosurgery, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061 China.
Qing SongCardiovascular Research Institute and Department of Medicine, Morehouse School of Medicine, Atlanta, GA, 30310 USA, 4DGENOME Inc, Atlanta, GA, 30033 USA and Center of Big Data and Bioinformatics, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061 China.

Funding

Morehouse School of Medicine Center of Excellence Research Endowment ProgramS21MD000101 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI MONTGOMERY-RICE, VALERIE C. · 2001 to 2015
$74.3M
TRANSCRIPTION FACTORS AND PROSTATE CANCERG12RR003034 · NCRR · MOREHOUSE SCHOOL OF MEDICINE · PI ZHAO, XUEYING · 1986 to 2011
$32.4M
Research Desogn and Biostatistics CoreU54MD007588 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI MAYBERRY, ROBERT M · 2012 to 2018
$24.8M
TRANSPLANTATION OF EXOSOMES FROM HYPOXIA-PRECONDITIONED ADIPOSE-DERIVED STEM CELLS PROMOTES ANGIOGENESIS IN ISCHEMIC HEARTG12MD007602 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI BOND, VINCENT C · 2012 to 2017
$18.4M
Morehouse Cardiovascular Research Center of ExcellenceP50HL117929 · NHLBI · MOREHOUSE SCHOOL OF MEDICINE · PI TAYLOR, HERMAN ALFRED · 2013 to 2018
$6.7M
Determining the Phased Genome SequencesR21HG006173 · NHGRI · MOREHOUSE SCHOOL OF MEDICINE · PI SONG, QING · 2012 to 2013
$389k
Cost-effective and high-throughput chromosomal haplotypingR43HG007621 · NHGRI · 4DGENOME, INC. · PI SONG, QING · 2014 to 2014
$219k
NCRR NIH HHS 1 C06 RR07571NCRR NIH HHS G12 RR003034NCRR NIH HHS RR003034NHGRI NIH HHS R21HG006173NHGRI NIH HHS R43HG007621NHLBI NIH HHS HL117929NIMHD NIH HHS G12 MD007602NIMHD NIH HHS MD007602NIMHD NIH HHS S21 MD000101NIMHD NIH HHS U54 MD007588NIMHD NIH HHS U54MD07588
6 · The paper itself

Abstract

unlabelledWe present a software tool called GenomeLaser that determines the haplotypes of each person from unphased high-throughput genotypes in family pedigrees. This method features high accuracy, chromosome-range phasing distance, linear computing, flexible pedigree types and flexible genetic marker types. AVAILABILITY AND IMPLEMENTATION: http://www.4dgenome.com/software/genomelaser.html.

Indexed as

HaplotypesPedigreeSoftwareFemaleGenetic MarkersGenotypeGenotyping TechniquesHumansMaleGenetic Markers

Identifiers

PMID26286810
PMCPMC5013932

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.