Evidence map›Paper›PMID 26286573›Full record

ArticleBMC pediatrics2015

Bacterial meningitis in children under 15 years of age in Nepal.

Rajani Ghaju Shrestha, Sarmila Tandukar, Shamshul Ansari, Akriti Subedi, Anisha Shrestha, Rekha Poudel, Nabaraj Adhikari, Shital Raj Basnyat, Jeevan Bahadur Sherchand

Abstract read
In one paragraph

Article in BMC pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rajani Ghaju ShresthaPublic Health Research Laboratory, Institute of Medicine, Maharajgunj, Kathmandu, Nepal. rajani_ghaju12@hotmail.com.
Sarmila TandukarPublic Health Research Laboratory, Institute of Medicine, Maharajgunj, Kathmandu, Nepal. sar1234tan@gmail.com.
Shamshul AnsariDepartment of Microbiology, Chitwan Medical College, Bharatpur, Chitwan, Nepal. shamshulansari483@yahoo.com.
Akriti SubediKantipur College of Medical Science, Sitapaila, Kathmandu, Nepal. muskan4291@gmail.com.
Anisha ShresthaPublic Health Research Laboratory, Institute of Medicine, Maharajgunj, Kathmandu, Nepal. anishashrestha@gmail.com.
Rekha PoudelCentral Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal. rekhapoudel08@gmail.com.
Nabaraj AdhikariKantipur College of Medical Science, Sitapaila, Kathmandu, Nepal. adhikarinaba13@yahoo.com.
Shital Raj BasnyatKantipur College of Medical Science, Sitapaila, Kathmandu, Nepal. shitalrajbasnet@yahoo.com.
Jeevan Bahadur SherchandPublic Health Research Laboratory, Institute of Medicine, Maharajgunj, Kathmandu, Nepal. jivansherchand@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBacterial meningitis in children is a life-threatening problem resulting in severe morbidity and mortality. For the prompt initiation of antibacterial therapy, rapid and reliable diagnostic methods are of utmost importance. Therefore, this study was designed to find out the rate of bacterial pathogens of meningitis from suspected cases by performing conventional methods and latex agglutination.

methodsA descriptive type of study was carried out from May 2012 to April 2013. Cerebrospinal fluid (CSF) specimens from 252 suspected cases of meningitis were subjected for Gram staining, bacterial culture and latex agglutination test. The identification of growth of bacteria was done following standard microbiological methods recommended by American Society for Microbiology. Antibiotic sensitivity testing was done by modified Kirby-Bauer disk diffusion method.

resultsFrom the total 252 suspected cases, 7.2 % bacterial meningitis was revealed by Gram staining and culture methods whereas latex agglutination method detected 5.6 %. Gram-negative organisms contributed the majority of the cases (72.2 %) with Haemophilus influenzae as the leading pathogen for meningitis. Overall, 33.3 % mortality rate was found.

conclusionsIn conclusion, a significant rate of bacterial meningitis was found in this study prompting concern for national wide surveillance.

Indexed as

AdolescentAnti-Bacterial AgentsBacteriaBacteriological TechniquesChildChild, PreschoolFemaleGentian VioletHumansInfantInfant, NewbornLatex Fixation TestsMaleMeningitis, BacterialMicrobial Sensitivity TestsNepalAnti-Bacterial AgentsGentian VioletGram's stainPhenazines

Identifiers

PMID26286573
PMCPMC4541735

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.