ReviewBMC ophthalmology2015
Cladosporium keratitis - a case report and literature review.
Review in BMC ophthalmology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Cladosporium halotolerans: Exploring an Unheeded Human Pathogen.Mycopathologia · 2023Pooled it
- Crescentic Hair Shaft Defects and Piedra-Like Lesions With Follicular Invasion in Northern Elephant Seals (Mirounga angustirostris).Veterinary dermatology · 2026Article
- Fungal keratitis caused by a dematiaceous Pleosporales member following ocular trauma with a wooden fragment: a case report.Journal of ophthalmic inflammation and infection · 2026Article
- Article
- Causative Agents of Fungal Keratitis in Northeastern Iran: A 3-Year Tertiary Care Hospital Study.The American journal of tropical medicine and hygiene · 2025Article
- Evaluating and Managing the Microbial Contamination of Eye Drops: A Two-Phase Hospital-Based Study.Pharmaceutics · 2024Article
- Eye fungal infections: a mini review.Archives of microbiology · 2023Review
- Review
- An Atypical Etiology of Fungal Keratitis Caused byJournal of fungi (Basel, Switzerland) · 2022Article
- First reported case ofIDCases · 2022Article
- Identification of the Fungal Community in Otomycosis by Internal Transcribed Spacer Sequencing.Frontiers in microbiology · 2022Article
- Determination of probability of causative pathogen in infectious keratitis using deep learning algorithm of slit-lamp images.Scientific reports · 2021Article
- The GenusMolecules (Basel, Switzerland) · 2021Review
- Voriconazole in the successful management of a case of Acanthamoeba-Cladosporium keratitis.American journal of ophthalmology case reports · 2021Article
- Unorthodox ophthalmic preparations on the Ghanaian market: a potential risk for ocular and enteric infections.African health sciences · 2020Article
- Influence of bacterial burden on meibomian gland dysfunction and ocular surface disease.Clinical ophthalmology (Auckland, N.Z.) · 2019Article
- Fungal keratitis caused by rare organisms.Journal of current ophthalmology · 2018Article
- Microplasma Jet Arrays as a Therapeutic Choice for Fungal Keratitis.Scientific reports · 2018Article
- The Interaction of Human Pathogenic Fungi With C-Type Lectin Receptors.Frontiers in immunology · 2018Review
- Fungal keratitis: study of increasing trend and common determinants.Nepal journal of epidemiology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFungal keratitis is one of the major causes of infectious keratitis in tropical countries. Symptoms of fungal keratitis consist of blurred vision, redness, tearing, photophobia, pain and foreign body sensation. If not treated effectively, it could lead to blindness. Common causes include Candida spp., Fusarium spp. and Aspergillus spp.. With the limited choices of topical antifungal agents, we were faced with Cladosporium keratitis, a rare cause of fungal keratitis. CASE PRESENTATION: A 62-year-old Asian male construction worker came to us with intense ocular pain, injection of the conjunctiva, blurred vision, and foreign body sensation in his left eye. His visual acuity was 20/40 OD and 20/400 OS. Slit-lamp exam revealed a corneal ulcer with feathery margin and Descemet's membrane folding. The culture yielded Cladosporium species.. The patient did not show improvements after applying topical natamycin (5 %), topical amphotericin B (1mg/ml), topical fluconazole (2mg/ml) and oral ketoconazole (200mg). After shifting the medical regimen to voriconazole via topical and systemic routes (1mg/ml and 200mg respectively), the keratitis was controlled.
conclusionsFungal keratitis remains a challenge for ophthalmologists as there is no evidence suggesting any particular drug or combination of drugs is more effective than another. A review of common topical antifungal agents was done. Voriconazole could be a good choice for treating corneal infection by Cladosporium species.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.