Evidence map›Paper›PMID 26286340›Full record

Observational studyInternational journal of clinical pharmacy2015

Adverse drug reactions experience in a teaching hospital in Jordan.

Mohammed Alsbou, Sameh Alzubiedi, Hamed Alzobi, Nawal Abu Samhadanah, Yousef Alsaraireh, Omar Alrawashdeh, Amin Aqel, Khalil Al-Salem

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in International journal of clinical pharmacy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Patterns of adverse drug reactions (ADRs) in Saudi Arabia.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2022
    Article
  5. Article
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mohammed AlsbouDepartment of Pharmacology, Faculty of Medicine, Mutah University, Al-Karak, Jordan. Mohsb74@yahoo.com.
Sameh AlzubiediDepartment of Clinical Pharmacy and Biopharmaceutics, Faculty of Pharmacy, Jordan University, Amman, Jordan.
Hamed AlzobiDepartment of Microbiology and Immunology, Faculty of Medicine, Mutah University, Al-Karak, Jordan.
Nawal Abu SamhadanahDepartment of Continuous Medical Education, Alkarak Governmental Hospital, Al-Karak, Jordan.
Yousef AlsarairehDepartment of Pharmacology, Faculty of Medicine, Mutah University, Al-Karak, Jordan.
Omar AlrawashdehDepartment of Anatomy, Faculty of Medicine, Mutah University, Al-Karak, Jordan.
Amin AqelDepartment of Microbiology and Immunology, Faculty of Medicine, Mutah University, Al-Karak, Jordan.
Khalil Al-SalemDepartment of Ophthalmology, Faculty of Medicine, Mutah University, Al-Karak, Jordan.
Mutah University · JOUniversity of Jordan · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdverse drug reactions (ADRs) represent a major health care problem.

objectiveTo identify the most common ADRs, drugs implicated in ADRs, and to assess their causality, severity, preventability and risk factors predisposing to reported ADRs in Jordan.

settingAl-Karak teaching hospital, southern of Jordan. Method A cross sectional observational study was carried out for 11 months from January to November 2013. Suspected ADRs were recorded in ADRs report forms and analyzed for causality, severity, and preventability.

main outcome measureMost common ADRs, drugs involved in these ADRs, causality, severity, and preventability of suspected ADRs.

resultsA total of 64 reports were received. Some patients suffered more than one ADR. The total number of ADRs identified was 108. Forty one drugs were involved in causing these ADRs. About 2/3 of adverse reactions (73.4 %) did not cause admission to the hospital, whereas 26.6 % of the ADRs resulted in admission. Majority of the ADRs were type A (62.5 %). Most of ADRs (92.2 %) were assessed as probable. Nearly, 65.6 % of ADRs were categorized as mild. Majority of ADRs were assessed as "not preventable" (75 %). The most common classes of drugs involved in ADRs were antibiotics, analgesics, vaccines and antiepileptics. The most commonly identified ADRs were abdominal pain, skin rash, shortness of breath, fever, upper gastrointestinal bleeding and vomiting. Risk factors contributed to ADRs were age and polypharmacy.

conclusionJordanian healthcare providers should be aware of the importance of detecting and reporting ADRs, in order to prevent and reduce the incidence of ADRs. Awareness of risk factors predisposing to ADRs may help in identifying patients with higher risk and therefore reducing the risk of these ADRs and improving patient outcome.

Indexed as

AdolescentAdultAdverse Drug Reaction Reporting SystemsAgedChildChild, PreschoolCross-Sectional StudiesDrug-Related Side Effects and Adverse ReactionsFemaleHospitals, TeachingHumansIncidenceInfantJordanMaleMiddle AgedAdverse drug reactionsJordanPharmacovigilance

Identifiers

PMID26286340
OpenAlexW1780828359

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.