Evidence map›Paper›PMID 26286085›Full record

ArticlePediatric radiology2016

Infantile encephalitic beriberi: magnetic resonance imaging findings.

Nisar A Wani, Umar A Qureshi, Majid Jehangir, Kaiser Ahmad, Waseem Ahmad

Abstract read
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In one paragraph

Article in Pediatric radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
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  8. Wernicke's encephalopathy in exclusive breastfed infants.World journal of pediatrics : WJP · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nisar A WaniDepartment of Pediatric Radiology, Government Medical College Srinagar, Jammu and Kashmir, Pin, 190010, India. ahmad77chinar@gmail.com.
Umar A QureshiDepartment of Pediatrics, Government Medical College Srinagar, Jammu and Kashmir, India.
Majid JehangirDepartment of Radiology, Government Medical College Srinagar, Jammu and Kashmir, India.
Kaiser AhmadDepartment of Pediatrics, Government Medical College Srinagar, Jammu and Kashmir, India.
Waseem AhmadDepartment of Pediatrics, Government Medical College Srinagar, Jammu and Kashmir, India.
Government Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThiamine deficiency in infants is still encountered in developing countries. It may present with acute neurological manifestations of infantile encephalitic beriberi.

objectiveTo review brain MRI findings in infantile encephalitic beriberi from a single institution. MATERIALS AND

methodsA retrospective review of MRI scans in 22 infants with acute-onset beriberi encephalopathy was carried out.

resultsHyperintense lesions on T2-weighted images were seen symmetrically in the putamen in all patients, in the caudate nuclei in 16/22 (73%), the thalami in 7/22 (32%) and the globi pallidi in 3/22 (14%) of the infants. Altered signal intensity lesions in the cerebral cortex were seen in 7/22 (32%). The mammillary bodies were seen in one infant and the periaqueductal gray matter in two. There was restricted diffusion in 14/22 (64%), and 6/8 children with no evidence of restriction had been imaged ≥10 days after presentation. MR spectroscopy showed increased lactate peak in 6/8 infants (75%).

conclusionRecognition of symmetrical T2-W hyperintense lesions in the basal ganglia with restricted diffusion and prominent lactate peak may allow early diagnosis of encephalitic beriberi in at-risk infants.

Indexed as

BrainChildChild, PreschoolFemaleHumansInfantMagnetic Resonance ImagingMaleReproducibility of ResultsSensitivity and SpecificityWernicke EncephalopathyBasal gangliaInfantile encephalitic beriberiInfantsMagnetic resonance imagingMagnetic resonance spectroscopyThiamineWernicke encephalopathy

Identifiers

PMID26286085
OpenAlexW1485439668

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.