Evidence map›Paper›PMID 26285801›Full record

ArticleScientific reports2015

Histone H3K4me3 and H3K27me3 regulatory genes control stable transmission of an epimutation in rice.

Xiangsong Chen, Xiaoyun Liu, Yu Zhao, Dao-Xiu Zhou

Abstract read
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Understanding epigenomics based on the rice model.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020
    Review
  9. Article
  10. Article
  11. The gymnastics of epigenomics in rice.Plant cell reports · 2018
    Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiangsong ChenNational Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, 430070 Wuhan, China.
Xiaoyun Liu1] National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, 430070 Wuhan, China [2] Institute for Interdisciplinary Scientific Research, Jianghan University, 430056 Wuhan, China.
Yu ZhaoNational Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, 430070 Wuhan, China.
Dao-Xiu Zhou1] National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, 430070 Wuhan, China [2] Institute Plant Science Paris-Saclay (IPS2), Université Paris-sud 11, 91405 Orsay, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA methylation loss can produce inheritable active epialleles in plants. The mechanism involved in the stable transmission of hypomethylated epimuations is presently not clear. Here we show that maintenance of a stably hypomethylated active epiallele in rice required a CHD3 protein (CHR729) and that over-expression of an H3K4me3 demethylase (JMJ703) or H3K27me3 methyltransferase (SDG711) could stably resilence the epiallele. CHR729 and JMJ703 have antagonistic function in H3K4me3 in maintaining the active state of the epiallele, whereas SDG711-mediated H3K27me3 was sufficient to stably repress the locus. The data suggest that H3K4me3 and H3K27me3 controlled by these chromatin regulators may be involved in stable transmission/resetting of epigenetic variation in rice.

Indexed as

Gene Expression Regulation, PlantGenes, PlantAllelesDNA, BacterialDNA MethylationHistonesInheritance PatternsLysineMethylationMutationOryzaPlant ProteinsPlants, Genetically ModifiedTissue Culture TechniquesDNA, BacterialHistonesLysinePlant ProteinsT-DNA

Identifiers

PMID26285801
PMCPMC4541256

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.