ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2015
Reference values for cerebral blood flow velocities in critically ill, sedated children.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 35 citations in OpenAlex.
- Pediatric MOGAD in the Intensive Care Unit: A Case Series.Neurocritical care · 2026Article
- The brain shock index: repurposing the Lindegaard ratio for detecting cerebral hypoperfusion in children with cerebral malaria.The ultrasound journal · 2025Article
- Advances in Point-of-Care Ultrasound in Pediatric Acute Care Medicine.Indian journal of pediatrics · 2025Review
- Neuromonitoring in Pediatric Neurocritical Care: An Introduction.Neurocritical care · 2024Article
- Cerebrovascular dynamics after pediatric traumatic brain injury.Frontiers in physiology · 2023Article
- Cerebral vasospasm in children with subarachnoid hemorrhage: frequency, diagnosis, and therapeutic management.Neurocritical care · 2022Article
- Transcranial Doppler Ultrasound, a Review for the Pediatric Intensivist.Children (Basel, Switzerland) · 2022Review
- Low Dosing Norepinephrine Effects on Cerebral Oxygenation and Perfusion During Pediatric Shock.Frontiers in pediatrics · 2022Article
- A Survey of Neuromonitoring Practices in North American Pediatric Intensive Care Units.Pediatric neurology · 2022Article
- Clinical applications of transcranial Doppler in non-trauma critically ill children: a scoping review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Article
- Practice Recommendations for Transcranial Doppler Ultrasonography in Critically Ill Children in the Pediatric Intensive Care Unit: A Multidisciplinary Expert Consensus Statement.Journal of pediatric intensive care · 2021Article
- Transcranial Doppler Use in Non-traumatic Critically Ill Children: A Multicentre Descriptive Study.Frontiers in pediatrics · 2021Article
- Transcranial Doppler ultrasound findings in children with moderate-to-severe traumatic brain injury following abusive head trauma.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
- The Effect of the Relationship of APOE Polymorphisms and Cerebral Vasospasm on Functional Outcomes in Children With Traumatic Brain Injury.Biological research for nursing · 2018Article
- Cerebral Blood Flow Following Hybrid Stage I Palliation in Infants with Hypoplastic Left Heart Syndrome.Pediatric cardiology · 2018Article
- Relationships between cerebral flow velocities and neurodevelopmental outcomes in children with moderate to severe traumatic brain injury.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018Observational
- Transcranial Doppler Ultrasound Use in Pediatric Traumatic Brain Injury.Journal of radiology nursing · 2017Article
- Anatomical and Physiological Differences between Children and Adults Relevant to Traumatic Brain Injury and the Implications for Clinical Assessment and Care.Frontiers in neurology · 2017Review
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTranscranial Doppler ultrasound (TCD) is increasingly being used in the pediatric intensive care unit to assess cerebral hemodynamics during critical illness. However, no normative data in this patient population have been published to date. Therefore, we aimed to describe the anterior and posterior cerebral blood flow velocities in critically ill children undergoing mechanical ventilation and sedation.
designA prospective, observational cohort study was performed. Children with known or suspected acute or chronic neurologic conditions were excluded. Participants underwent TCD measurement of middle cerebral and basilar artery flow velocities.
resultsOne hundred and forty children newborn to 17 years of age were enrolled. Measured values were lower in this cohort of children than the previously published cerebral flow velocities of normal, healthy children.
conclusionsCerebral blood flow velocities of the basal cerebral arteries in critically ill, mechanically ventilated, sedated children are lower than in healthy children of the same age and gender published in previous studies. As such, the cerebral blood flow velocity (CBFV) values reported here may serve as a more accurate reference point when using TCD as a clinical tool to diagnose CBFV abnormalities and guide therapy in this patient population.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.