ArticleIndian journal of pharmacology
Study of acute transfusion reactions in a teaching hospital of Sikkim: A hemovigilance initiative.
Article in Indian journal of pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 35 citations in OpenAlex.
- Frequency of Acute Adverse Transfusion Reactions at King Saud Medical City, Riyadh, Saudi Arabia.Journal of clinical medicine · 2026Article
- Transfusion practices, thresholds, and complications in pediatric oncology patients: a single-center prospective longitudinal observational study.Frontiers in pediatrics · 2026Article
- A ten-year hemovigilance report in the regional blood transfusion center of Sfax (Tunisia).La Tunisie medicale · 2025Article
- Retrospective Audit of Transfusion Reactions in a Tertiary-Care Hospital in South India.Cureus · 2024Article
- Blood component-associated acute transfusion reactions in pediatric patients: experience of a tertiary care hospital.Turkish journal of medical sciences · 2024Article
- Retrospective evaluation of acute transfusion reactions in a tertiary hospital in Erzurum, Turkey.Northern clinics of Istanbul · 2021Article
- Surveillance of Transfusion Related Adverse Reactions in a Tertiary Care Centre in Bangalore: A 4-Year Hemovigilance Initiative.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2020Article
- Analysis of Patterns of Adverse Transfusion Reactions and Management: A Novel Initiative toward Hemovigilance in a Teaching Hospital of South India.Journal of laboratory physicians · 2020Article
- Incidence and Analysis of 7 Years Adverse Transfusion Reaction: A Retrospective Analysis.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2020Article
- Haemovigilance: A Current Update in Indian Perspective.Journal of clinical and diagnostic research : JCDR · 2016Review
- Transfusion-related adverse reactions in pediatric and surgical patients at a tertiary care teaching hospital in India.Asian journal of transfusion scienceArticle
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveBlood transfusions are inherently associated with risks ranging in severity from minor to life-threatening. Continuous monitoring of transfusion related complications can promote understanding of factors contributing to transfusion reactions and help to formulate necessary remedial measures. This study was designed to analyze the frequency and nature of transfusion reactions reported to the blood bank of a remote North East Indian teaching hospital. MATERIALS AND
methodsAll acute transfusion reactions (ATRs) reported to the blood bank over a period of 20 months (May 2013 to January 2015) were reviewed and analyzed. The risk of transfusion reactions associated with each individual component was assessed.
resultsA total of 3455 units of whole blood and component transfusions were carried out of which a total of 32 (0.92%) ATRs were encountered. Packed red blood cells (PRBCs) (n = 15, P = 0.06) and whole blood (WB) (n = 13, P = 0.83) were most commonly implicated. Allergic reaction was the most frequent transfusion reaction encountered (65.6%), seen most commonly with PRBC (risk of 0.76%, P = 0.42), and WB (risk of 0.68%, P = 0.63) transfusions. This was followed by febrile reactions (28.1%), which were seen more commonly with PRBCs (risk of 0.57%, P = 0.016). No reactions were observed with platelet transfusions.
conclusionThe overall incidence of transfusion reactions in this hospital is slightly higher than those having more advanced transfusion facilities in India. The lack of leukoreduction facilities in our hospital could be a likely cause for the same. The use of leukoreduced WB and PRBCs could possibly reduce the overall incidence of ATRs in general and febrile nonhemolytic transfusion reactions in particular.
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