SynthesisPloS one2015
Spatial/Frontal QRS-T Angle Predicts All-Cause Mortality and Cardiac Mortality: A Meta-Analysis.
Synthesis in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07196891 (Prognostic Value of the Frontal QRS/T Angle for 28-day Mortality and Neurological Outcomes in Aneurysmal Subarachnoid Hemorrhage), which is not on this map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prognostic Value of the Frontal QRS/T Angle for 28-day Mortality and Neurological Outcomes in Aneurysmal Subarachnoid Hemorrhage
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Total cosine R-to-T for predicting ventricular arrhythmic and mortality outcomes: A systematic review and meta-analysis.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2018Pooled it
- Electrophysiological Markers in Hypertrophic Cardiomyopathy: Enhancing Sudden Cardiac Death Risk Prediction with Index of Cardiac Electrophysiological Balance and Its Corrected Variant.Anatolian journal of cardiology · 2026Article
- Effect of sodium-glucose cotransporter-2 inhibitors on electrocardiographic markers of ventricular repolarization: A systematic review and meta-analysis.American heart journal plus : cardiology research and practice · 2026Review
- Association of the Uric Acid-to-Magnesium Ratio and Frontal QRS-T Angle with Angiographic Coronary Disease Severity in Acute Coronary Syndrome.Journal of clinical medicine · 2026Article
- Uric Acid-to-Magnesium Ratio as a Novel Biomarker of Angiographic Coronary Artery Disease Burden: A Retrospective Cross-Sectional Comparative Analysis with the Uric Acid-to-HDL Ratio and Frontal QRS-T Angle in Patients Undergoing Elective Coronary Angiography.Journal of cardiovascular development and disease · 2026Article
- Electro-Mechanical Cardiac Remodeling in Metabolic Syndrome: Association Between Frontal QRS-T Angle and Subclinical Left Ventricular Dysfunction Assessed by Four-Dimensional Echocardiography.Journal of clinical medicine · 2026Article
- Predictive value of frontal QRS-T angle for no-reflow phenomenon in patients with acute coronary syndrome.BMC cardiovascular disorders · 2026Article
- Empowering genetic discoveries and cardiovascular risk assessment by predicting electrocardiograms from genotype.NPJ digital medicine · 2026Article
- The Synergistic Relationship Between Erectile Dysfunction and Frontal QRS-T Angle in Predicting Coronary Artery Disease Severity: A Prospective Observational Study.Anatolian journal of cardiology · 2025Observational
- A Novel Electrocardiographic Index to Predict the Severity of Coronary Calcification.Anatolian journal of cardiology · 2025Article
- A new electrocardiographic evaluation in hyperkalemia: frontal QRS-T angle.Irish journal of medical science · 2025Article
- Electrocardiogram-based machine learning for risk stratification of patients with suspected acute coronary syndrome.European heart journal · 2025Observational
- Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease.Nature communications · 2023Article
- The Relationship between the Frontal QRS-T Angle on ECG and Physical Activity Level in Young Adults.International journal of environmental research and public health · 2023Article
- Correlation between frontal QRS-T angle, Tp-e interval, and Tp-e/QT ratio to coronary artery severity assessed with SYNTAX score in stable coronary artery disease patients.Journal of arrhythmia · 2022Article
- Deep-Learning-Based Estimation of the Spatial QRS-T Angle from Reduced-Lead ECGs.Sensors (Basel, Switzerland) · 2022Article
- The Relationship between Insulin Resistance and Spatial QRS-T Angle in American Adults.Acta Cardiologica Sinica · 2021Article
- A Method to Minimise the Impact of ECG Marker Inaccuracies on the Spatial QRS-T angle: Evaluation on 1,512 Manually Annotated ECGs.Biomedical signal processing and control · 2021Article
- Effects of Newly Developed Right Versus Left Bundle Branch Block on the QRS Axis, T-wave Axis and Frontal QRS-T Angle in Patients with a Narrow QRS.Internal medicine (Tokyo, Japan) · 2021Article
- Diagnostic and prognostic values of the QRS-T angle in patients with suspected acute decompensated heart failure.ESC heart failure · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA number of studies have assessed the predictive effect of QRS-T angles in various populations since the last decade. The objective of this meta-analysis was to evaluate the prognostic value of spatial/frontal QRS-T angle on all-cause death and cardiac death.
methodsPubMed, EMBASE, and the Cochrane Central Register of Controlled Trials were searched from their inception until June 5, 2014. Studies reporting the predictive effect of spatial/frontal QRS-T angle on all-cause/cardiac death in all populations were included. Relative risk (RR) was used as a measure of effect.
resultsTwenty-two studies enrolling 164,171 individuals were included. In the combined analysis in all populations, a wide spatial QRS-T angle was associated with an increase in all-cause death (maximum-adjusted RR: 1.40; 95% confidence interval [CI]: 1.32 to 1.48) and cardiac death (maximum-adjusted RR: 1.71; 95% CI: 1.54 to 1.90), a wide frontal QRS-T angle also predicted a higher rate of all-cause death (maximum-adjusted RR: 1.71; 95% CI: 1.54 to 1.90). Largely similar results were found using different methods of categorizing for QRS-T angles, and similar in subgroup populations such as general population, populations with suspected coronary heart disease or heart failure. Other stratified analyses and meta-analyses using unadjusted data also generated consistent findings.
conclusionsSpatial QRS-T angle held promising prognostic value on all-cause death and cardiac death. Frontal QRS-T angle was also a promising predictor of all-cause death. Given the good predictive value of QRS-T angle, a combined stratification strategy in which QRS-T angle is of vital importance might be expected.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.