ArticlePloS one2015
A Novel Multiparametric Approach to 3D Quantitative MRI of the Brain.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Time-efficient, high-resolution 3T whole-brain relaxometry using Cartesian 3D MR Spin TomogrAphy in Time-Domain (MR-STAT) with cerebrospinal fluid suppression.Magnetic resonance in medicine · 2025Article
- Synthetic MR: Clinical applications in neuroradiology.Neuroradiology · 2025Review
- In vivo demonstration of globotriaosylceramide brain accumulation in Fabry Disease using MR Relaxometry.Neuroradiology · 2024Article
- A comprehensive protocol for quantitative magnetic resonance imaging of the brain at 3 Tesla.PloS one · 2024Article
- Artificial intelligence and radiation effects on brain tissue in glioblastoma patient: preliminary data using a quantitative tool.La Radiologia medica · 2023Article
- Giant Tumefactive Perivascular Space: Advanced Fusion MR Imaging and Tractography Study-A Case Report and a Systematic Review.Diagnostics (Basel, Switzerland) · 2023Article
- MR Imaging Signs of Gadolinium Retention Are Not Associated with Long-Term Motor and Cognitive Outcomes in Multiple Sclerosis.AJNR. American journal of neuroradiology · 2023Article
- Primary Multiparametric Quantitative Brain MRI: State-of-the-Art Relaxometric and Proton Density Mapping Techniques.Radiology · 2022Review
- Synthetic MRI for Radiotherapy Planning for Brain and Prostate Cancers: Phantom Validation and Patient Evaluation.Frontiers in oncology · 2022Article
- A Comparison of Magnetic Resonance Imaging Methods to Assess Multiple Sclerosis Lesions: Implications for Patient Characterization and Clinical Trial Design.Diagnostics (Basel, Switzerland) · 2021Article
- Unraveling Deep Gray Matter Atrophy and Iron and Myelin Changes in Multiple Sclerosis.AJNR. American journal of neuroradiology · 2021Article
- Medical physics challenges in clinical MR-guided radiotherapy.Radiation oncology (London, England) · 2020Review
- Voxel-based analysis of gray matter relaxation rates shows different correlation patterns for cognitive impairment and physical disability in relapsing-remitting multiple sclerosis.NeuroImage. Clinical · 2020Article
- MRI features suggestive of gadolinium retention do not correlate with Expanded Disability Status Scale worsening in Multiple Sclerosis.Neuroradiology · 2019Article
- Brain tissue volumes and relaxation rates in multiple sclerosis: implications for cognitive impairment.Journal of neurology · 2019Article
- Determinants of Deep Gray Matter Atrophy in Multiple Sclerosis: A Multimodal MRI Study.AJNR. American journal of neuroradiology · 2019Article
- Neuroimaging in Fabry disease: current knowledge and future directions.Insights into imaging · 2018Review
- Longitudinal Assessment of Dentate Nuclei Relaxometry during Massive Gadobutrol Exposure.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2018Article
- A 3D two-point method for whole-brain water content and relaxation time mapping: Comparison with gold standard methods.PloS one · 2018Article
- Redefining the Pulvinar Sign in Fabry Disease.AJNR. American journal of neuroradiology · 2017Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Magnetic Resonance properties of tissues can be quantified in several respects: relaxation processes, density of imaged nuclei, magnetism of environmental molecules, etc. In this paper, we propose a new comprehensive approach to obtain 3D high resolution quantitative maps of arbitrary body districts, mainly focusing on the brain. The theory presented makes it possible to map longitudinal (R1), pure transverse (R2) and free induction decay ([Formula: see text]) rates, along with proton density (PD) and magnetic susceptibility (χ), from a set of fast acquisition sequences in steady-state that are highly insensitive to flow phenomena. A novel denoising scheme is described and applied to the acquired datasets to enhance the signal to noise ratio of the derived maps and an information theory approach compensates for biases from radio frequency (RF) inhomogeneities, if no direct measure of the RF field is available. Finally, the results obtained on sample brain scans of healthy controls and multiple sclerosis patients are presented and discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.