ArticleIranian journal of public health2015
Serum 25-Hydroxyvitamin D in Patients with Major Depressive Disorder.
Article in Iranian journal of public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Role of dietary factors in the prevention and treatment for depression: an umbrella review of meta-analyses of prospective studies.Translational psychiatry · 2021Pooled it
- Glycemic index, glycemic load, and depression: a systematic review and meta-analysis.European journal of clinical nutrition · 2019Pooled it
- Dietary Inflammatory Potential and the Risk of Incident Depression in Adults: A Systematic Review.Advances in nutrition (Bethesda, Md.) · 2019Pooled it
- Vitamin D Mitigates Depression-related Disorders in an Animal Model of Depression: A Behavioral, Anatomopahtological, and Molecular Investigation, Implicating the Hippocampal BDNF Signaling Pathway.Central nervous system agents in medicinal chemistry · 2025Article
- Review
- Adherence to the Mediterranean diet and depression, anxiety, and stress symptoms in Chilean university students: a cross-sectional study.Cadernos de saude publica · 2023Article
- 25(OH)D levels are decreased in patients with difficult-to-treat depression.Comprehensive psychoneuroendocrinology · 2022Article
- Vitamin D Doses from Solar Ultraviolet and Dietary Intakes in Patients with Depression: Results of a Case-Control Study.Nutrients · 2020Article
- Vitamin D and inflammation in major depressive disorder.Journal of affective disorders · 2020Article
- The cellular and molecular basis of major depressive disorder: towards a unified model for understanding clinical depression.Molecular biology reports · 2020Review
- Egg consumption and prevalence of psychological disorders in adults.European journal of nutrition · 2019Article
- Association of circulating 25-hydroxyvitamin D with mental well-being in a population-based, nationally representative sample of German adolescents.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2016Article
Corrections and comments
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Authors and funding
3 authors.
Funding
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Abstract
backgroundWe investigated the association between serum 25(OH) D levels and depressive symptoms in patients with major depressive disorder (MDD).
methodsEighty-five adults, 44 drug free patients with MDD and 41 apparently healthy controls, participated in the study. The Hamilton Depression Rating Scale was used to assess severity of major depression. Mental health of the controls was assessed according to DSM-IV criteria. Stress level of the participants was assessed by the Holmes and Rahe stress scale. Serum 25(OH) D levels was measured by immunochemiluminescence assay. Vitamin D deficiency was defined as a serum 25(OH) D concentration of lower than 20 ng/ml.
resultsDepressed patients had the higher levels of stress. There was a positive correlation between stress level and disease severity (r= 0.32, P= 0.03). In total participants, mean percentage of vitamin D deficiency was 77.6% with 75% in patients and 80.5% in the healthy subjects. There were no differences between the two groups in serum 25(OH) D levels and percentage of subjects with the vitamin deficiency. A negative correlation was observed between disease severity and serum 25(OH) D level of patients with depression episodes < 2 y (r= -0.38, P = 0.08) and winter samples (samples collected and measured from December to march, r= -0.62, P = 0.004).
conclusionSerum 25(OH) D levels were not associated with depression. However, the inverse relationship between levels of vitamin D and depressive symptoms in current depression episodes and in sun-deprived season warrants further investigation.
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26284211PMC4537627What OpenQuestion holds
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