ReviewFrontiers in plant science2015
Physiological implications of arginine metabolism in plants.
Review in Frontiers in plant science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 234 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
234 citing papers in PubMed, 615 citations in OpenAlex.
- Metabolic Profile ofPlants (Basel, Switzerland) · 2026Article
- Effects of ectomycorrhizal fungi on the physiological and ecological characteristics of Larix gmelinii under salt stress.Mycorrhiza · 2026Article
- Unique N-acetyl-L-glutamate kinase of Prasinoderma coloniale: new features of an old enzyme.Planta · 2026Article
- Alterations in Arginase Activity and Polyamine Metabolism Contribute to the Mode of Action of Canavanine in Tomato Roots.Biology · 2026Article
- Calcium, methyl jasmonate and their combined foliar applications: Influence on Tempranillo grape amino acids composition over two seasons.Journal of the science of food and agriculture · 2026Article
- Bacillus amyloliquefaciens-induced resistance against the olive knot disease: An integrated transcriptomic and metabolomic analysis.Pest management science · 2026Article
- DNA Methylation Shapes Seed-Borne Microbiome and Proteome Responses During Early Maize-Beneficial Bacteria Interactions.Plant, cell & environment · 2026Article
- The progression of leaf senescence is gated by the cytosolic arginine pool.Nature plants · 2026Article
- Desiccation-Induced Oxidative Stress Causes Metabolic Flux in the Terrestrial Green Alga Trentepohlia sp., Suggesting Extensive Metabolic Reprogramming for Stress Adaptation.Applied biochemistry and biotechnology · 2026Article
- The cytosolic arginine pool represses the progression of leaf senescence.Nature plants · 2026Article
- Non-Targeted Metabolomic Analyses Provide Insights into Exogenous Trehalose-Mediated Heat Stress Tolerance in Tea Plants (Plants (Basel, Switzerland) · 2026Article
- Integrated Metabolomics and Transcriptomics Analysis of Exogenous Arginine-Mediated Sucrose Accumulation in Sugarcane.International journal of molecular sciences · 2026Article
- Host-dependent variation in free amino acid profiles and physiological responses enhancing drought tolerance in Santalum album.Scientific reports · 2026Article
- Novel cytoplasmic male sterile line development and stage-specific metabolomic profiling in rice (Oryza sativa L.) for advancing hybrid breeding technology.BMC plant biology · 2026Article
- Foliar L-arginine and seaweed extract mitigate salinity stress in Calendula officinalis L. by enhancing physiological and biochemical performance.BMC plant biology · 2026Article
- Advances in the Application of Amino Acids in the Preservation of Postharvest Fruits and Vegetables.Foods (Basel, Switzerland) · 2026Review
- An Inclusive Insight into leaf Metabolome Reveals Substantial Metabolic flux in Maize Seedlings Subjected to Boron (B) Toxicity.Applied biochemistry and biotechnology · 2026Article
- Characterization ofJournal of fungi (Basel, Switzerland) · 2026Article
- Article
- Structural basis for pH-responsive amino acid transport via SLC7A4.Nature communications · 2026Article
174 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nitrogen is a limiting resource for plant growth in most terrestrial habitats since large amounts of nitrogen are needed to synthesize nucleic acids and proteins. Among the 21 proteinogenic amino acids, arginine has the highest nitrogen to carbon ratio, which makes it especially suitable as a storage form of organic nitrogen. Synthesis in chloroplasts via ornithine is apparently the only operational pathway to provide arginine in plants, and the rate of arginine synthesis is tightly regulated by various feedback mechanisms in accordance with the overall nutritional status. While several steps of arginine biosynthesis still remain poorly characterized in plants, much wider attention has been paid to inter- and intracellular arginine transport as well as arginine-derived metabolites. A role of arginine as alternative source besides glutamate for proline biosynthesis is still discussed controversially and may be prevented by differential subcellular localization of enzymes. Apparently, arginine is a precursor for nitric oxide (NO), although the molecular mechanism of NO production from arginine remains unclear in higher plants. In contrast, conversion of arginine to polyamines is well documented, and in several plant species also ornithine can serve as a precursor for polyamines. Both NO and polyamines play crucial roles in regulating developmental processes as well as responses to biotic and abiotic stress. It is thus conceivable that arginine catabolism serves on the one hand to mobilize nitrogen storages, while on the other hand it may be used to fine-tune development and defense mechanisms against stress. This review summarizes the recent advances in our knowledge about arginine metabolism, with a special focus on the model plant Arabidopsis thaliana, and pinpoints still unresolved critical questions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.