Evidence map›Paper›PMID 26283932›Full record

ArticleFrontiers in systems neuroscience2015

Advancing brain-machine interfaces: moving beyond linear state space models.

Adam G Rouse, Marc H Schieber

Open access · goldAbstract read
In one paragraph

Article in Frontiers in systems neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
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  6. Spatiotemporal Distribution of Location and Object Effects in Primary Motor Cortex Neurons during Reach-to-Grasp.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Adam G RouseDepartment of Neurology, University of Rochester Rochester, NY, USA ; Department of Neurobiology and Anatomy, University of Rochester Rochester, NY, USA ; Department of Biomedical Engineering, University of Rochester Rochester, NY, USA.
Marc H SchieberDepartment of Neurology, University of Rochester Rochester, NY, USA ; Department of Neurobiology and Anatomy, University of Rochester Rochester, NY, USA ; Department of Biomedical Engineering, University of Rochester Rochester, NY, USA.
University of Rochester · US

Funding

Variation in Throughput from Single Motor Cortex Neurons to MusclesR01NS065902 · NINDS · UNIVERSITY OF ROCHESTER · PI SCHIEBER, MARC H · 2010 to 2014
$1.8M
Reach, Grasp, and ManipulationR01NS079664 · NINDS · UNIVERSITY OF ROCHESTER · PI SCHIEBER, MARC H · 2012 to 2016
$1.7M
NINDS NIH HHS R01 NS065902NINDS NIH HHS R01 NS079664
6 · The paper itself

Abstract

Advances in recent years have dramatically improved output control by Brain-Machine Interfaces (BMIs). Such devices nevertheless remain robotic and limited in their movements compared to normal human motor performance. Most current BMIs rely on transforming recorded neural activity to a linear state space composed of a set number of fixed degrees of freedom. Here we consider a variety of ways in which BMI design might be advanced further by applying non-linear dynamics observed in normal motor behavior. We consider (i) the dynamic range and precision of natural movements, (ii) differences between cortical activity and actual body movement, (iii) kinematic and muscular synergies, and (iv) the implications of large neuronal populations. We advance the hypothesis that a given population of recorded neurons may transmit more useful information than can be captured by a single, linear model across all movement phases and contexts. We argue that incorporating these various non-linear characteristics will be an important next step in advancing BMIs to more closely match natural motor performance.

Indexed as

brain-computer interfacehandkinematic synergymotor cortexmovement phasemuscle synergyneuroprostheticsnull space

Identifiers

PMID26283932
PMCPMC4516874
OpenAlexW1539784878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.