Evidence map›Paper›PMID 26283523›Full record

ArticleDiagnostic microbiology and infectious disease2015

Analytical performance of the automated multianalyte point-of-care mariPOC® for the detection of respiratory viruses.

Sara Sanbonmatsu-Gámez, Mercedes Pérez-Ruiz, Ana Lara-Oya, Irene Pedrosa-Corral, Cristina Riazzo-Damas, José María Navarro-Marí

Registry-linked trialOpen access · greenAbstract readEvaluation Study
In one paragraph

Article in Diagnostic microbiology and infectious disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03233516 (Trial of Respiratory Infections in Children for Enhanced Diagnostics), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03233516 completednot on this mapstarted 2017, after this paper: background citation

Trial of Respiratory Infections in Children for Enhanced Diagnostics

Typeobservational_patient_registrySponsorKarolinska InstitutetRan2017 to 2019Enrolled376ConditionsCommunity-acquired Pneumonia
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Modern Tools for Rapid Diagnostics of Antimicrobial Resistance.Frontiers in cellular and infection microbiology · 2020
    Review
  6. Article
  7. Review
  8. Article
  9. Point-of-care diagnostics for respiratory viral infections.Expert review of molecular diagnostics · 2018
    Review
  10. Article
  11. [Rapid diagnostic test for respiratory infections].Enfermedades infecciosas y microbiologia clinica · 2017
    Review
  12. Article
  13. Rapid diagnostic methods for acute viral respiratory infections.Enfermedades infecciosas y microbiologia clinica
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sara Sanbonmatsu-GámezServicio de Microbiología, Hospital Universitario Virgen de las Nieves, Avenida de las Fuerzas Armadas 2, 18012 Granada, Spain; Instituto de Investigación Biosanitaria de Granada, Calle Dr Azpitarte 4, 18012 Granada, Spain. Electronic address: saral.sanbonmatsu.sspa@juntadeandalucia.es.
Mercedes Pérez-RuizServicio de Microbiología, Hospital Universitario Virgen de las Nieves, Avenida de las Fuerzas Armadas 2, 18012 Granada, Spain; Instituto de Investigación Biosanitaria de Granada, Calle Dr Azpitarte 4, 18012 Granada, Spain.
Ana Lara-OyaServicio de Microbiología, Hospital Universitario Virgen de las Nieves, Avenida de las Fuerzas Armadas 2, 18012 Granada, Spain.
Irene Pedrosa-CorralServicio de Microbiología, Hospital Universitario Virgen de las Nieves, Avenida de las Fuerzas Armadas 2, 18012 Granada, Spain; Instituto de Investigación Biosanitaria de Granada, Calle Dr Azpitarte 4, 18012 Granada, Spain.
Cristina Riazzo-DamasServicio de Microbiología, Hospital Universitario Virgen de las Nieves, Avenida de las Fuerzas Armadas 2, 18012 Granada, Spain.
José María Navarro-MaríServicio de Microbiología, Hospital Universitario Virgen de las Nieves, Avenida de las Fuerzas Armadas 2, 18012 Granada, Spain; Instituto de Investigación Biosanitaria de Granada, Calle Dr Azpitarte 4, 18012 Granada, Spain.
Hospital Universitario Virgen de las Nieves · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The analytical performance of mariPOC® respi test (ArcDia® Laboratories, Turku, Finland) was evaluated using nucleic acid amplification techniques (NAATs) as the gold standard. The mariPOC assay allows automated detection of antigens from 8 respiratory viruses: influenza A and B viruses, respiratory syncytial virus, adenovirus, human metapneumovirus, and parainfluenza viruses 1-3. Positive results from samples with high viral load are available in 20min. Nasopharyngeal aspirates (n=192) from patients with acute respiratory infection and from previously positive samples were analyzed by mariPOC and NAATs (Simplexa(TM) FluA/FluB & RSV kit [n=118] and Luminex® Respiratory virus panel xTAG® RVP FAST [n=74]). Sensitivity, specificity, positive predictive value, and negative predictive value of mariPOC were 85.4%, 99.2%, 95.9%, and 97%, respectively, and 84.6% of positive results were reported in 20min. The good analytical performance and extended portfolio of mariPOC show this rapid assay as a good alternative for the etiological diagnosis of acute respiratory infection in laboratories that are not equipped with molecular assays.

Indexed as

Point-of-Care SystemsAdolescentAdultAgedAged, 80 and overAntigens, ViralAutomation, LaboratoryChildFemaleHumansImmunoassayInfant, NewbornMiddle AgedNasopharynxPredictive Value of TestsRespiratory Tract InfectionsAntigens, Viralantigen detectionpoint-of-carerapid testRespiratory virus

Identifiers

PMID26283523
PMCPMC7132759
OpenAlexW1878870772

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.