ArticleProceedings of the National Academy of Sciences of the United States of America2015
SUMOylation of phytochrome-B negatively regulates light-induced signaling in Arabidopsis thaliana.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed.
- Twenty-five years of photobodies: formation, composition, and the 2-compartment logic of phytochrome B signaling.Plant physiology · 2026Review
- Intragenic suppressor screen of YHB identifies novel and known loss-of-function alleles of Arabidopsis phytochrome B.bioRxiv : the preprint server for biology · 2026Article
- The C-terminal SUMOylation-dependent regulation of αKNL2 governs its centromere targeting and interaction with CENH3.Plant communications · 2026Article
- Article
- Charting the evolutionary path of the SUMO modification system in plants reveals molecular hardwiring of development to stress adaptation.The Plant cell · 2024Review
- Phytochrome B photobodies are comprised of phytochrome B and its primary and secondary interacting proteins.Nature communications · 2023Article
- Expression, Purification, and Enzymatic Analysis of Plant SUMO Proteases.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Phytochrome B enhances seed germination tolerance to high temperature by reducing S-nitrosylation of HFR1.EMBO reports · 2022Article
- The conjugation of SUMO to the transcription factor MYC2 functions in blue light-mediated seedling development in Arabidopsis.The Plant cell · 2022Article
- Linkage mapping combined with GWAS revealed the genetic structural relationship and candidate genes of maize flowering time-related traits.BMC plant biology · 2022Article
- Functional analysis ofFrontiers in plant science · 2022Article
- Article
- Phototropin Interactions with SUMO Proteins.Plant & cell physiology · 2021Article
- Phytochrome Signaling Networks.Annual review of plant biology · 2021Review
- Understanding the molecular mechanisms of trade-offs between plant growth and immunity.Science China. Life sciences · 2021Review
- Out of the Dark and Into the Light: A New View of Phytochrome Photobodies.Frontiers in plant science · 2021Review
- An Insight into the Factors Influencing Specificity of the SUMO System in Plants.Plants (Basel, Switzerland) · 2020Review
- Regulation of Aluminum Resistance in Arabidopsis Involves the SUMOylation of the Zinc Finger Transcription Factor STOP1.The Plant cell · 2020Article
- SIZ1-Mediated SUMO Modification of SEUSS Regulates Photomorphogenesis inPlant communications · 2020Article
- Defining the function of SUMO system in pod development and abiotic stresses in Peanut.BMC plant biology · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
9 authors.
Funding
Abstract
The red/far red light absorbing photoreceptor phytochrome-B (phyB) cycles between the biologically inactive (Pr, λmax, 660 nm) and active (Pfr; λmax, 730 nm) forms and functions as a light quality and quantity controlled switch to regulate photomorphogenesis in Arabidopsis. At the molecular level, phyB interacts in a conformation-dependent fashion with a battery of downstream regulatory proteins, including PHYTOCHROME INTERACTING FACTOR transcription factors, and by modulating their activity/abundance, it alters expression patterns of genes underlying photomorphogenesis. Here we report that the small ubiquitin-like modifier (SUMO) is conjugated (SUMOylation) to the C terminus of phyB; the accumulation of SUMOylated phyB is enhanced by red light and displays a diurnal pattern in plants grown under light/dark cycles. Our data demonstrate that (i) transgenic plants expressing the mutant phyB(Lys996Arg)-YFP photoreceptor are hypersensitive to red light, (ii) light-induced SUMOylation of the mutant phyB is drastically decreased compared with phyB-YFP, and (iii) SUMOylation of phyB inhibits binding of PHYTOCHROME INTERACTING FACTOR 5 to phyB Pfr. In addition, we show that OVERLY TOLERANT TO SALT 1 (OTS1) de-SUMOylates phyB in vitro, it interacts with phyB in vivo, and the ots1/ots2 mutant is hyposensitive to red light. Taken together, we conclude that SUMOylation of phyB negatively regulates light signaling and it is mediated, at least partly, by the action of OTS SUMO proteases.
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