ArticleProceedings of the National Academy of Sciences of the United States of America2015
Transforming growth factor-β signaling is constantly shaping memory T-cell population.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed.
- Monocyte-derived galectin-1Nature immunology · 2026Article
- Temporal Dissection of TGF-β signaling reveals differential impact during female reproductive mucosal CD8 resident memory T cell differentiation.Mucosal immunology · 2026Article
- TGF-β Regulates CD8Cells · 2026Article
- TGF-beta promotes human T follicular helper cell stemness properties at the expense of effector function.Frontiers in immunology · 2026Article
- CCR2Cellular & molecular immunology · 2025Article
- Age-Dependent Bi-Phasic Dynamics of Ly49Aging cell · 2025Article
- Double, double toil and trouble: transforming growth factor beta (TGF-β) in HIV infection.Frontiers in immunology · 2025Review
- TGF-β blockade drives a transitional effector phenotype in T cells reversing SIV latency and decreasing SIV reservoirs in vivo.Nature communications · 2024Article
- TGF-β broadly modifies rather than specifically suppresses reactivated memory CD8 T cells in a dose-dependent manner.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- TGF-β Signaling Prevents MHC Class II-Expressing Lymphatic Endothelial Cells from Reactivating Human Allogenic Memory CD4+ T Cells.Journal of immunology (Baltimore, Md. : 1950) · 2023Article
- Lung dopaminergic nerves facilitate the establishment of TThe Journal of allergy and clinical immunology · 2023Article
- Review
- The diverse effects of transforming growth factor-β and SMAD signaling pathways during the CTL response.Frontiers in immunology · 2023Review
- Improved memory CD8 T cell response to delayed vaccine boost is associated with a distinct molecular signature.Frontiers in immunology · 2023Article
- Inflammatory Cytokines That Enhance Antigen Responsiveness of Naïve CD8International journal of molecular sciences · 2022Article
- TGF-β-dependent lymphoid tissue residency of stem-like T cells limits response to tumor vaccine.Nature communications · 2022Article
- TGF-β regulates the stem-like state of PD-1+ TCF-1+ virus-specific CD8 T cells during chronic infection.The Journal of experimental medicine · 2022Article
- TGF-β promotes stem-like T cells via enforcing their lymphoid tissue retention.The Journal of experimental medicine · 2022Article
- Spatial, temporal and molecular dynamics of swine influenza virus-specific CD8 tissue resident memory T cells.Mucosal immunology · 2022Article
- Cellular senescence is a key mediator of lung aging and susceptibility to infection.Frontiers in immunology · 2022Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The long-term maintenance of memory T cells is essential for successful vaccines. Both the quantity and the quality of the memory T-cell population must be maintained. The signals that control the maintenance of memory T cells remain incompletely identified. Here we used two genetic models to show that continuous transforming growth factor-β signaling to antigen-specific T cells is required for the differentiation and maintenance of memory CD8(+) T cells. In addition, both infection-induced and microbiota-induced inflammation impact the phenotypic and functional identity of memory CD8(+) T cells.
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