ArticleBMC complementary and alternative medicine2015
Evaluation of the wound healing property of Commiphora guidottii Chiov. ex. Guid.
Article in BMC complementary and alternative medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 42 citations in OpenAlex.
- Efficacy and safety of myrrh in patients with incomplete abortion: a randomized, double-blind, placebo-controlled clinical study.BMC complementary medicine and therapies · 2020Trial
- In Vitro Evaluation of Antileishmanial Activity of Commiphora myrrha Essential Oil Nanoliposome.Veterinary medicine and science · 2026Article
- In Vivo Wound Healing and Antimicrobial Activities of the Hydroalcoholic Extract and Solvent Fractions ofBioMed research international · 2025Article
- Myrrh sitz bath for wound healing after hemorrhoidectomy: A retrospective study of adverse effects and treatment outcomes.Health science reports · 2024Article
- Characterization and comparative evaluation of wound healing potential of Ajugarin I andFrontiers in chemistry · 2023Article
- Role of Herbal Extracts of Catechu fromPharmaceuticals (Basel, Switzerland) · 2022Article
- Wound Healing Activity of 80% Methanolic Crude Extract and Solvent Fractions of the Leaves ofJournal of experimental pharmacology · 2022Article
- Investigation of Wound Healing and Anti-Inflammatory Activities of Solvent Fractions of 80% Methanol Leaf Extract ofJournal of inflammation research · 2021Article
- Histopathological evaluation of latex of Bellaco-Caspi,Veterinary world · 2020Article
- Cytotoxic Evaluation and Anti-Angiogenic Effects of Two Furano-Sesquiterpenoids fromMolecules (Basel, Switzerland) · 2020Article
- In Vivo Evaluation of Wound Healing and Anti-Inflammatory Activity of 80% Methanol Crude Flower Extract ofEvidence-based complementary and alternative medicine : eCAM · 2020Article
- Article
- Human neonatal stem cell-derived skin substitute improves healing of severe burn wounds in a rat model.Cell biology international · 2019Article
- Integrative Dermatology - The Use of Herbals and Nutritional Supplements to Treat Dermatological Conditions.Open access Macedonian journal of medical sciences · 2018Review
- Commercial Essential Oils as Potential Antimicrobials to Treat Skin Diseases.Evidence-based complementary and alternative medicine : eCAM · 2017Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe traditional use of the oleo-gum-resin of Commiphora guidottii Chiov. ex. Guid., which is commonly called scented myrrh, for topical treatment of wound is well documented. The major objective of the present study was to investigate the essential oil and resin obtained from C. guidottii for their potential wound healing properties. Due to their influence on the wound healing process, the anti-inflammatory and antimicrobial activities of scented myrrh have also been investigated.
methodsPowdered oleo-gum-resin of C. guidottii was steam-distilled to obtain essential oil, and the resin was extracted from the marc with MeOH and filtered. The TLC fingerprint profile of the resin has been recorded by using silica gel GF254 as stationary phase. The essential oil components were identified and quantified by GC-MS. Ointments prepared from the essential oil (4% v/w) and the resin (5% w/w) were used for wound healing activity tests. Toxicity of the formulated ointments was investigated according to Draize skin irritation test. Acute anti-inflammatory effect in mice was evaluated using carrageenan induced mouse hind paw oedema model. Antimicrobial activity tests were carried out using disk diffusion and broth dilution techniques against 21 pathogenic bacterial and 4 fungal strains.
resultsOintment formulations of both the oil and resin were found to be non-irritant at the concentrations used and showed significant (p<0.05-0.001) increase in wound contraction rate, shorter epithelization time and higher skin breaking strength as compared to the negative control. Overall, the antibacterial and antifungal activities of the oil and resin were comparable with the standard antibiotics ciprofloxacin and griseofulvin, respectively.
conclusionThe results confirm that scented myrrh possesses genuine wound healing activity supporting the traditional use of the plant.
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