Evidence map›Paper›PMID 26283140›Full record

ArticleInternational journal of obesity (2005)2016

LAP-BAND for BMI 30-40: 5-year health outcomes from the multicenter pivotal study.

J B Dixon, L L Eaton, V Vincent, R Michaelson

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in International journal of obesity (2005), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Experienced Weight Stigma Changes Following Bariatric Surgery: a Systematic Review and Meta-Analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Pooled it
  2. Depressive symptoms at short-, medium-, and long-term follow-up after bariatric surgical procedures: A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Pooled it
  3. Overview on the endoscopic treatment for obesity: A review.World journal of gastroenterology · 2023
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Medical devices for the treatment of obesity.Nature reviews. Gastroenterology & hepatology · 2017
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

J B DixonClinical Obesity Research, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia.
L L EatonUltaMed Corporation, Huntington Beach, CA, USA.
V VincentVernon Vincent Consulting, Santa Barbara, CA, USA.
R MichaelsonNorthwest Surgical Weight Loss, Everett, WA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe performed a 5-year multicenter study to evaluate the safety and effectiveness of the LAP-BAND System surgery (LBS) in patients with obesity with a body mass index (BMI) of 30-39.9 kg m(-)(2). This pivotal study was designed to support LBS application to the US Food and Drug Administration for broadening the indications for surgery and the lower BMI indication was approved with 1-year data in 2011, with the intention to complete the 5-year evaluation.

objectivesTo present broad health outcome data including weight change, patient reported outcomes, comorbidity change and complications during the 5-year study.

settingThe study was conducted at seven US private practice clinical trial sites.

methodsWe enrolled 149 BMI 30-39.9 subjects into a 5-year, multicenter, longitudinal, prospective post-approval study. Data for those completing each time point are presented.

resultsThe predefined target of at least 30% excess weight loss was achieved by more than 76% of subjects by 1-year and at every year thereafter during the 5-year study. Mean percentage weight loss at 5 years was 15.9±12.4%. Sustained weight loss was accompanied by sustained improvement in generic and weight-specific quality of life, symptoms of depression and the prevalence of binge-eating disorder. The number of subjects with normal fasting triglyceride, high-density lipoprotein cholesterol, plasma glucose and HbA1c increased significantly between baseline and 5 years. Fifty-four months after LBS implantation, the rate of device explants without replacement was 5.4%; however, the rate of explants increased to 12.1% by month 60 owing to no cost-elective band removals offered to subjects at study exit. No deaths or unanticipated adverse device effects were reported.

conclusionsThe LBS is safe and effective for people with BMI 30-39.9 with demonstrated improvements in weight loss, comorbidities and quality of life, and with a low explant rate through 5 years following treatment.

Indexed as

GastroplastyLaparoscopyAdultBlood GlucoseBlood PressureBody Mass IndexDyslipidemiasFemaleHumansLongitudinal StudiesMaleObesity, MorbidProspective StudiesQuality of LifeTreatment OutcomeUnited StatesBlood Glucose

Identifiers

PMID26283140

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.