Evidence map›Paper›PMID 26282794›Full record

ReviewJournal of the American Academy of Dermatology2015

Primary immunodeficiency update: Part I. Syndromes associated with eczematous dermatitis.

Dominique C Pichard, Alexandra F Freeman, Edward W Cowen

Open access · greenAbstract readReview
In one paragraph

Review in Journal of the American Academy of Dermatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Italian pediatric experts' consensus statement on diagnosis and management of primary atopic disorders.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Dominique C PichardNational Institutes of Health, National Cancer Institute, Bethesda, Maryland.
Alexandra F FreemanNational Institute of Allergy and Infectious Disease, Bethesda, Maryland.
Edward W CowenNational Institutes of Health, National Cancer Institute, Bethesda, Maryland. Electronic address: cowene@mail.nih.gov.
National Cancer Institute · USNational Institute of Allergy and Infectious Diseases · USNational Institutes of Health · US

Funding

Genes And Gene Products As ImmunoadjuvantsZIAAI000647 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI HOLLAND, STEVEN · 2009 to 2025
$22.6M
Dermatology Consultation ServiceZIDBC011317 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI COWEN, EDWARD · 2010 to 2021
$6.4M
Intramural NIH HHS ZID BC011317
6 · The paper itself

Abstract

In the past decade, the availability of powerful molecular techniques has accelerated the pace of discovery of several new primary immunodeficiencies (PIDs) and revealed the biologic basis of other established PIDs. These genetic advances, in turn, have facilitated more precise phenotyping of associated skin and systemic manifestations and provide a unique opportunity to better understand the complex human immunologic response. These continuing medical education articles will provide an update of recent advances in PIDs that may be encountered by dermatologists through their association with eczematous dermatitis, infectious, and non-infectious cutaneous manifestations. Part I will discuss new primary immunodeficiencies that have an eczematous dermatitis. Part II will focus on primary immunodeficiencies that greatly increase susceptibility to fungal infection and the noninfectious presentations of PIDs.

Indexed as

ComorbidityEczemaEducation, Medical, ContinuingFemaleGenetic TherapyHumansImmunologic Deficiency SyndromesIncidenceMalePrognosisRisk AssessmentSeverity of Illness IndexTreatment Outcome

Identifiers

PMID26282794
PMCPMC4542006
OpenAlexW2154020221

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.