ArticleMicrobial ecology in health and disease2015
Indole - the scent of a healthy 'inner soil'.
Article in Microbial ecology in health and disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Association between AHR in EGCs and IBS-D patients: the indole pathway of tryptophan metabolism.Frontiers in nutrition · 2025Article
- Gut metabolic changes during pregnancy reveal the importance of gastrointestinal region in sample collection.Metabolomics : Official journal of the Metabolomic Society · 2024Article
- Dietary L-Tryptophan consumption determines the number of colonic regulatory T cells and susceptibility to colitis via GPR15.Nature communications · 2023Article
- Review
- What If Not All Metabolites from the Uremic Toxin Generating Pathways Are Toxic? A Hypothesis.Toxins · 2022Review
- Article
- Fleeting Beauty-The World of Plant Fragrances and Their Application.Molecules (Basel, Switzerland) · 2021Review
- Targeting Dietary and Microbial Tryptophan-Indole Metabolism as Therapeutic Approaches to Colon Cancer.Nutrients · 2021Review
- Dissecting Individual Interactions between Pathogenic and Commensal Bacteria within a Multispecies Gut Microbial Community.mSphere · 2021Article
- Multi-strain volatile profiling of pathogenic and commensal cutaneous bacteria.Scientific reports · 2020Article
- Identification of Genetic VariantsFrontiers in microbiology · 2020Article
- Identification of QTL for perenniality and floral scent in cowpea (Vigna unguiculata [L.] Walp.).PloS one · 2020Article
- Tryptophan Co-Metabolism at the Host-Pathogen Interface.Frontiers in immunology · 2020Article
- Microbiome: An Emerging New Frontier in Graft-Versus-Host Disease.Digestive diseases and sciences · 2019Review
- The Role of the Canine Gut Microbiome and Metabolome in Health and Gastrointestinal Disease.Frontiers in veterinary science · 2019Review
- Substantial Extracellular Metabolic Differences Found Between Phylogenetically Closely Related Probiotic and Pathogenic Strains ofFrontiers in microbiology · 2019Article
- Unexpected differential metabolic responses of Campylobacter jejuni to the abundant presence of glutamate and fucose.Metabolomics : Official journal of the Metabolomic Society · 2018Article
- Coprophagy in nineteenth-century psychiatry.Microbial ecology in health and disease · 2018Article
- Probiotic lactic acid bacteria - the fledgling cuckoos of the gut?Microbial ecology in health and disease · 2016Article
- Biodiversity of Intestinal Lactic Acid Bacteria in the Healthy Population.Advances in experimental medicine and biology · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tryptophan is an essential amino acid with an indole nucleus. Humans cannot produce this amino acid themselves, but must obtain it through their diet. Much attention is currently paid to the wide physiological and clinical implications of the tryptophan-derived substances, serotonin and kynurenines, generated by human enzymes following the intestinal absorption of tryptophan. However, even before being absorbed, several microbial metabolites of tryptophan are formed, mainly from 'malabsorbed' (incompletely digested) proteins within the colon. The normal smell of human faeces is largely due to indole, one of the major metabolites. Recent studies indicate that this foul-smelling substance is also of utmost importance for our health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.