Evidence map›Paper›PMID 26282505›Full record

ArticlePediatric surgery international2015

Safety of surgery for neonatal congenital diaphragmatic hernia as reflected by arterial blood gas monitoring: thoracoscopic versus open repair.

Tadaharu Okazaki, Manabu Okawada, Hiroyuki Koga, Go Miyano, Takashi Doi, Yuki Ogasawara, Yuta Yazaki, Kinya Nishimura, Eiichi Inada, Geoffrey J Lane and 1 more

Abstract readComparative Study
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In one paragraph

Article in Pediatric surgery international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Diagnosis and management of congenital diaphragmatic hernia: a clinical practice guideline.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2018
    Guideline
  5. Review
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tadaharu OkazakiDepartment of Pediatric Surgery, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu, Chiba, 279-0021, Japan. okazakit@juntendo.ac.jp.
Manabu OkawadaDepartment of Pediatric Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Hiroyuki KogaDepartment of Pediatric Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Go MiyanoDepartment of Pediatric Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Takashi DoiDepartment of Pediatric Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Yuki OgasawaraDepartment of Pediatric Surgery, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu, Chiba, 279-0021, Japan.
Yuta YazakiDepartment of Pediatric Surgery, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu, Chiba, 279-0021, Japan.
Kinya NishimuraDepartment of Anesthesiology, Juntendo University School of Medicine, Tokyo, Japan.
Eiichi InadaDepartment of Anesthesiology, Juntendo University School of Medicine, Tokyo, Japan.
Geoffrey J LaneDepartment of Pediatric Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Atsuyuki YamatakaDepartment of Pediatric Surgery, Juntendo University School of Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe monitored arterial blood gases during thoracoscopic (TR) and open repair (OR) of congenital diaphragmatic hernia (CDH) to assess the safety of intraoperative hypercapnia and acidosis.

methodsWe reviewed 30 neonatal CDH cases (OR = 10, TR = 20) diagnosed prenatally or within 6 h of birth at out institution from 2002 to 2014 not requiring inhaled nitric oxide (NO) intraoperatively. OR, routine until 2006 was replaced by TR in 2007. All subjects were managed identically.

resultsFive TR cases requiring conversion to OR were excluded. Prenatal diagnosis, gestational age at birth, gender, birth weight, and side of CDH were similar. Preoperative PaCO2 and pH were not significantly different. However, while intraoperative increase in mean PaCO2 (38.8-62.8 mmHg; p < 0.01) and decrease in mean pH (7.44-7.25; p < 0.01) were significant in TR, intraoperative PaCO2 was <70 mmHg in 12/15 cases and intraoperative pH was >7.20 in 11/15 cases. Both PaCO2 and pH reverted to normal on completion of surgery; pre- and postoperative results were comparable. There were no postoperative complications.

conclusionsIt would appear that neonatal cases of CDH not requiring NO can tolerate TR, despite transient reversible deterioration in acid/base balance, indicating that TR is safe for the treatment of selected cases of CDH.

Indexed as

ThoracoscopyBlood Gas AnalysisFemaleHernias, Diaphragmatic, CongenitalHumansInfant, NewbornMaleMonitoring, PhysiologicPostoperative ComplicationsPregnancyPrenatal DiagnosisAcidemiaCongenital diaphragmatic herniaHypercapniaThoracoscopic repair

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.