Evidence map›Paper›PMID 26282285›Full record

ArticleThe Journal of allergy and clinical immunology2016

GATA3 haploinsufficiency does not block allergic sensitization or atopic disease.

Monica G Lawrence, Jennifer W Leiding, Jonathan J Lyons, Amy P Hsu, Celeste C Nelson, Nina Jones, Alan Fitzgerald, Wade W Chien, Lisa Workman, Thomas A Platts-Mills and 5 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of allergy and clinical immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. CD4 T Helper Cell Subsets and Related Human Immunological Disorders.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Monica G LawrenceAsthma and Allergic Diseases Center, University of Virginia Health System, Charlottesville, Va.
Jennifer W LeidingLaboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Md; Division of Allergy, Immunology, and Rheumatology, Department of Pediatrics, University of South Florida, St Petersburg, Fla.
Jonathan J LyonsLaboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Md.
Amy P HsuLaboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Md.
Celeste C NelsonLaboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Md.
Nina JonesClinical Research Directorate/CMRP, Leidos Biomedical Research, Inc, National Laboratory for Cancer Research, Frederick, Md.
Alan FitzgeraldLaboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Md.
Wade W ChienDivision of Intramural Research, National Institute on Deafness and Other Communication Disorders, NIH, Bethesda, Md; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, Md.
Lisa WorkmanAsthma and Allergic Diseases Center, University of Virginia Health System, Charlottesville, Va.
Thomas A Platts-MillsAsthma and Allergic Diseases Center, University of Virginia Health System, Charlottesville, Va.
Carmen BrewerDivision of Intramural Research, National Institute on Deafness and Other Communication Disorders, NIH, Bethesda, Md.
Rachel I GafniNational Institute of Dental and Craniofacial Research, NIH, Bethesda, Md.
Kelly D StoneLaboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Md.
Joshua D MilnerLaboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Md.
Steven M HollandLaboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Md. Electronic address: smh@nih.gov.

Funding

Clinical Analysis Of Disorders Of Hearing And BalanceZIADC000064 · NIDCD · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · PI HERTZANO, RONNA · 2009 to 2025
$25.2M
Genes And Gene Products As ImmunoadjuvantsZIAAI000647 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI HOLLAND, STEVEN · 2009 to 2025
$22.6M
Transgenic Animal Models Of Human Immune DefectsZIAAI000646 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI HOLLAND, STEVEN · 2009 to 2025
$22.2M
Neurotology ProgramZIADC000082 · NIDCD · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · PI HERTZANO, RONNA · 2012 to 2025
$17.7M
Genetic and Pathophysiologic Study of Atopic DiseaseZIAAI001183 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MILNER, JOSHUA · 2013 to 2019
$8.7M
DUST MITE, COCKROACH AND CAT ALLERGENS IN HOUSES/ASTHMAR01AI020565 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI PLATTS-MILLS, THOMAS A. · 1985 to 2017
$7.1M
GENES AND GENE PRODUCTS AS IMMUNOADJUVANTSZ01AI000647 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI HOLLAND, STEVEN M · 1992 to 2008
$5.4M
CCR NIH HHS HHSN261200800001CIntramural NIH HHS Z01 AI000647NCI NIH HHS HHSN261200800001ENIAID NIH HHS R01 AI020565
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HaploinsufficiencyAllergensGATA3 Transcription FactorHumansHypersensitivityHypersensitivity, ImmediateImmunoglobulin ESkin TestsT-Lymphocyte SubsetsAllergensGATA3 Transcription FactorImmunoglobulin E

Identifiers

PMID26282285
PMCPMC4747849

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.