Evidence map›Paper›PMID 26281832›Full record

ArticleBMC psychiatry2015

Measuring depression with CES-D in Chinese patients with type 2 diabetes: the validity and its comparison to PHQ-9.

Yuying Zhang, Rose Z W Ting, Marco H B Lam, Siu-Ping Lam, Roseanne O Yeung, Hairong Nan, Risa Ozaki, Andrea O Y Luk, Alice P S Kong, Yun-Kwok Wing and 2 more

Registry-linked trialAbstract readComparative StudyValidation Study
In one paragraph

Article in BMC psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07305415 (Integrative Therapeutic Programme to Regulate Expressed Emotions Among Informal Caregivers of People With Dementia), which is not on this map. Cited by 55 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07305415 narecruitingnot on this mapstarted 2025, after this paper: background citation

Integrative Therapeutic Programme to Regulate Expressed Emotions Among Informal Caregivers of People With Dementia: a Pilot Randomized Controlled Trial

TypeinterventionalSponsorThe University of Hong KongRan2025 to 2027Enrolled56ConditionsBPSD (Behavioral and Psycological Symptoms of Dementia), Expressed Emotion, Depressive Symptom, Caregiving StressArmsCaregivers Of dementia Processing Emotions (COPE)
3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  5. Measurement properties of depression questionnaires in patients with diabetes: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yuying ZhangDepartment of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, China. jennyzhang@adf.org.hk.
Rose Z W TingDepartment of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, China. pigpig350@gmail.com.
Marco H B LamDepartment of Psychiatry, The Chinese University of Hong Kong, Hong Kong SAR, China. lhb352@ha.org.hk.
Siu-Ping LamDepartment of Psychiatry, The Chinese University of Hong Kong, Hong Kong SAR, China. joycelam@cuhk.edu.hk.
Roseanne O YeungDepartment of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, China. roseanne.yeung@gmail.com.
Hairong NanHong Kong Institute of Diabetes and Obesity, Hong Kong SAR, China. nan.fang08@gmail.com.
Risa OzakiDepartment of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, China. risaozaki@cuhk.edu.hk.
Andrea O Y LukDepartment of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, China. andrealuk@cuhk.edu.hk.
Alice P S KongDepartment of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, China. alicekong@cuhk.edu.hk.
Yun-Kwok WingDepartment of Psychiatry, The Chinese University of Hong Kong, Hong Kong SAR, China. ykwing@cuhk.edu.hk.
Norman SartoriusThe Association for the Improvement of Mental Health Programmes, Geneva, Switzerland. sartorius@normansartorius.com.
Juliana C N ChanDepartment of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, China. jchan@cuhk.edu.hk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe validity of the 20-item Center for Epidemiological Studies Depression (CES-D) scale for depression screening in Hong Kong Chinese patients with type 2 diabetes remains unknown. We aimed to validate CES-D, compare its psychometric properties with the 9-item Patient Health Questionnaire (PHQ-9), and explore whether one of the two is more suitable for depression screening in Chinese patients with type 2 diabetes.

methodsBetween June 2010 and July 2011, 545 consecutive Chinese patients with type 2 diabetes who underwent structured comprehensive assessments completed the CES-D and PHQ-9. Forty patients were retested within 2-4 weeks by telephone interview and 97 patients were randomly selected to undergo the Mini International Neuropsychiatric Interview (MINI) by psychiatrists for clinical diagnosis of depression.

resultsThe internal consistency (Cronbach's α) of CES-D was 0.85, with a test-retest correlation coefficient of 0.64. The area under the curve for CES-D compared to the clinical diagnosis of major depression was 0.85. A cut-off score of ≥21 for CES-D provided the optimal balance between sensitivity (78.3 %) and specificity (74.3 %) and identified 17.8 % (n = 97) of patients with depression. CES-D and PHQ-9 showed moderate agreement in depression screening (Cohen's Kappa: 0.45). Compared to non-depressed patients, those who screened positive by PHQ-9 had a higher HbA1c whereas the glycemic differences were not significant when using CES-D.

conclusionThe CES-D is a valid screening tool for depression in Chinese type 2 diabetic patients although the PHQ-9 was more discriminative in identifying those with suboptimal glycemic control.

Indexed as

Psychiatric Status Rating ScalesAdultAgedAsian PeopleChinaDepressionDiabetes Mellitus, Type 2FemaleHumansMaleMiddle AgedPsychometricsReproducibility of Results

Identifiers

PMID26281832
PMCPMC4538746

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.