Evidence map›Paper›PMID 26281028›Full record

SynthesisCancer2015

Systematic review of acupuncture to control hot flashes in cancer patients.

M Kay Garcia, Leslie Graham-Getty, Robin Haddad, Yisheng Li, Jennifer McQuade, Richard T Lee, Michael Spano, Lorenzo Cohen

Abstract readSystematic Review
In one paragraph

Synthesis in Cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 4 pooled it
10.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Effects of non-pharmacological supportive care for hot flushes in breast cancer: a meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017
    Pooled it
  5. Acupuncture for reduction of symptom burden in multiple myeloma patients undergoing autologous hematopoietic stem cell transplantation: a randomized sham-controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Trial
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Inpatient Acupuncture at a Major Cancer Center.Integrative cancer therapies · 2018
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Oncology Advanced Practitioners and Breast Cancer Prevention.Journal of the advanced practitioner in oncology
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

M Kay GarciaIntegrative Medicine Program, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Leslie Graham-GettyAmerican College of Acupuncture and Oriental Medicine, Houston, Texas.
Robin HaddadIntegrative Medicine Program, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Yisheng LiDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Jennifer McQuadeIntegrative Medicine Program, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Richard T LeeIntegrative Medicine Program, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Michael SpanoIntegrative Medicine Program, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Lorenzo CohenIntegrative Medicine Program, The University of Texas MD Anderson Cancer Center, Houston, Texas.
The University of Texas MD Anderson Cancer Center · USAmerican College of Financial Services · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
TRAINING FOR ACADEMIC ONCOLOGY/HEMATOLOGYT32CA009666 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Michael Davies, Courtney DiNardo · 1994 to 2026
$9.8M
Placebo Controlled Trial Of Acupuncture To Prevent Radiation-Induced XerostomiaR01CA148707 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI COHEN, LORENZO · 2011 to 2014
$2.7M
Community-Based, Phase III Trial of acupuncture to treat chronic XerostomiaR01CA160880 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI COHEN, LORENZO · 2012 to 2017
$1.8M
NCI NIH HHS CA148707NCI NIH HHS CA160880NCI NIH HHS R01 CA148707NCI NIH HHS R01 CA160880NCI NIH HHS T32 CA009666
6 · The paper itself

Abstract

Hot flashes (HFs) are a common side effect of cancer treatment. The purpose of this systematic review was to evaluate evidence related to the use of acupuncture for HFs in cancer patients. EMBASE, MEDLINE, Cochrane (all databases), PubMed, the Cumulative Index to Nursing and Allied Health Literature, and Scopus were searched from their inception through December 2014. Included studies had to be randomized controlled trials with a usual-care and/or placebo comparison group that investigated acupuncture to treat HFs in cancer patients. No language limits were applied. The risk of bias (ROB) was rated as low, high, or unclear according to Cochrane criteria. Both within-group and between-group changes were evaluated. Four hundred two items were identified, and 192 duplicates were omitted; this left 210 publications to be screened. Eight studies met the inclusion criteria, and all involved women with breast cancer. All studies showed significant within-group improvement from the baseline for true acupuncture (TA). One study showed significant improvement in favor of TA over sham acupuncture (SA; P < .001), 1 study found in favor of TA over SA for nighttime HFs only (P = .03), and 1 study found in favor of TA over SA or untreated controls (P < .01 and P < .001, respectively). Between-group (TA vs SA) effect size (ES) estimates for daytime and nighttime HFs were calculated (ES range, 0.04-0.9) whenever possible. No studies were rated with a low ROB. In conclusion, the current level of evidence is insufficient to either support or refute the benefits of acupuncture for the management of HFs in cancer patients. Future studies should provide within-group and between-group ES estimates in addition to P values.

Indexed as

Acupuncture TherapyBreast NeoplasmsFemaleHot FlashesHumansRandomized Controlled Trials as Topicacupuncturecancerhot flasheshot flushesintegrative medicinesystematic review

Identifiers

PMID26281028
PMCPMC4635055
OpenAlexW2118013642

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.