ReviewChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2015
The human occipital bone: review and update on its embryology and molecular development.
Review in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 46 citations in OpenAlex.
- The developing spheno-occipital skull base: developmental variants and embryologic remnants that mimic pathology in children.Pediatric radiology · 2026Review
- Age estimation from the immature pars lateralis using decision tree analysis.International journal of legal medicine · 2026Article
- MRI-morphometric characterization of Chiari malformation types 0 and 1 with syringomyelia: implications for diagnosis and pathogenesis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Observational
- MRI-based quantification of primary ossification centers in the lateral and basilar parts of the human fetal occipital bone.BMC medical imaging · 2025Article
- A new golden ratio for foramen magnum in pre- and post-adolescent children.Scientific reports · 2025Article
- Geometric growth of the normal human craniocervical junction from 0 to 18 years old.Journal of anatomy · 2024Article
- Bony prominence and variations of the transverse sinus groove: novel anatomical findings in relation to sinus pathologies.Neurosurgical review · 2024Article
- Assessing the morphology and bone mineral density of the immature pars lateralis as an indicator of age.International journal of legal medicine · 2024Article
- Review
- Minimally invasive foramen magnum decompression using tubular retractors (MIFT) for Chiari I malformations.Acta neurochirurgica · 2023Article
- Article
- Prevalence of Mendosal Suture Patency in Infants Up to the Age of 18 Months.Plastic and reconstructive surgery. Global open · 2022Article
- Quantitative anatomy of the fused ossification center of the occipital squama in the human fetus.PloS one · 2021Article
- Alterations in skull base anatomy in intrauterine and postnatal repaired myelomeningoceles.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
- Chiari malformation type I: what information from the genetics?Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019Review
- Review
- Diameters and bone thickness at the margin of the foramen magnum in dry skulls from pediatric population: a cross-sectional anatomical study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017Article
- Midline occipital suture: a rare finding.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017Article
- Torcular pseudomass: a potential diagnostic pitfall in infants and young children.Pediatric radiology · 2017Article
- The modified occipital condyle screw: A quantitative anatomic study investigating the feasibility of a novel instrumented fixation technique for craniocervical fusion.Journal of craniovertebral junction & spineArticle
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe formation of the occipital bone is intricate and has been extensively studied with many controversial conclusions, but with minimal effort being focused on the genes and molecular interactions necessary for its formation. A better understanding of this bone of the calvarial and skull base may shed light on pathologies where the occiput is often considered the offending entity.
methodsA review of the germane medical literature using textbooks and standard search engines was performed to gather information about previous conclusions as it pertains to the embryology and ossification of the occipital bone.
resultsThe occipital bone has both membranous and cartilaginous origin with ossification occurring as early as week 9 of fetal gestation. Its formations is dependent on complex interacts between genes and molecules with pathologies resulting from disruption of this delicate process.
conclusionThere has been much controversy in the past in regards to the development and ossification process necessary for occipital bone formation, which has only recently been clarified with documentation of the genes and molecular interactions necessary for its formation. Lastly, this improved knowledge might improve our understanding of such congenital derailments as the Chiari malformations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.