Evidence map›Paper›PMID 26280316›Full record

ArticleJournal of artificial organs : the official journal of the Japanese Society for Artificial Organs2016

Comparison and preparation of multilayered polylactic acid fabric strengthen calcium phosphate-based bone substitutes for orthopedic applications.

Wen-Cheng Chen, Chia-Ling Ko, Jia-Kai Yang, Hui-Yu Wu, Jia-Horng Lin

Abstract read
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In one paragraph

Article in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wen-Cheng ChenAdvanced Medical Devices and Composites Laboratory, Department of Fiber and Composite Materials, Feng Chia University, 100, Wenhwa Rd., Seatwen, Taichung, 40724, Taiwan. wincheng0925@yahoo.com.tw.
Chia-Ling KoAdvanced Medical Devices and Composites Laboratory, Department of Fiber and Composite Materials, Feng Chia University, 100, Wenhwa Rd., Seatwen, Taichung, 40724, Taiwan.
Jia-Kai YangAdvanced Medical Devices and Composites Laboratory, Department of Fiber and Composite Materials, Feng Chia University, 100, Wenhwa Rd., Seatwen, Taichung, 40724, Taiwan.
Hui-Yu WuAdvanced Medical Devices and Composites Laboratory, Department of Fiber and Composite Materials, Feng Chia University, 100, Wenhwa Rd., Seatwen, Taichung, 40724, Taiwan.
Jia-Horng LinAdvanced Medical Devices and Composites Laboratory, Department of Fiber and Composite Materials, Feng Chia University, 100, Wenhwa Rd., Seatwen, Taichung, 40724, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An attempt to maintain the three-dimensional space into restorative sites through the conveniently pack porous fillers are general used strategy. Advancement in the manufacturing protective shells in the scaffolds, which would be filled with brittle ceramic grafts for the development of highly connective pores provides the approach to solve crack problem for generating the tissues. Therefore, multilayered braided and alkalized poly(lactic acid) (PLA) composites with calcium phosphate bone cement (CPC) were synthesized and compared. The PLA/CPC composites were divided into various groups according to a series of heat-treatment temperatures (100-190 °C) and periods (1-3 h) and then characterized. The effects of 24-h immersion on the strength decay resistance of the samples were compared. Results showed that the residual oil capped on the surfaces of alkalized PLA braid was removed, and the structure was unaltered. However, the reduced tensile stress of alkalized PLA braids was due to ester-group formation by hydrolysis. Mechanical test results of PLA/CPC composites showed that the strength significantly increased after heat treatment, except when the heating temperature was higher than the PLA melting point at approximately 160-170 °C. The degree of PLA after recrystallization became higher than that of unheated composites, thereby leading to reduced strength and toughness of the specimen. Braiding fibers of biodegradable PLA reinforced and toughened the structure particularly of the extra-brittle material of thin-sheet CPC after implantation.

Indexed as

Bone CementsLactic AcidMaterials TestingPolymersBone SubstitutesCalcium PhosphatesCeramicsPolyestersBone CementsBone SubstitutesCalcium PhosphatesLactic AcidPolyesterspoly(lactide)PolymersBone graftCalcium phosphate bone cement (CPC)Poly(lactic) acid (PLA)Protective shells

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.