ArticleParasitology research2015
Genetic characterization of livestock and human hydatid cyst isolates from northwest Iran, using the mitochondrial cox1 gene sequence.
Article in Parasitology research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Echinococcus granulosus sensu lato Genotypes in Different Hosts Worldwide: A Systematic Review.Acta parasitologica · 2022Pooled it
- A systematic review and meta-analysis of the genetic characterization of human echinococcosis in Iran, an endemic country.Epidemiology and health · 2019Pooled it
- Frequency and Sequence Analysis of Echinococcus granulosus Sensu Lato Isolated From Buffaloes in Northern Iran.Veterinary medicine and science · 2025Article
- Article
- Update on the genetic diversity and population structure of Echinococcus granulosus in Gansu Province, Tibet Autonomous Region, and Xinjiang Uygur Autonomous Region, Western China, inferred from mitochondrial cox1, nad1, and nad5 sequences.Parasitology research · 2023Article
- Survey and Molecular Characterization of Echinococcus granulosus sensu stricto from Livestock and Humans in the Altai Region of Xinjiang, ChinaPathogens (Basel, Switzerland) · 2023Article
- Proteomics investigation of human sera for determination of postoperative indicators of pulmonary cystic echinococcosis.Journal of cardiothoracic surgery · 2023Article
- Genetic characterization of human echinococcosis in Southern Punjab, Pakistan.Frontiers in cellular and infection microbiology · 2023Article
- Food-borne zoonotic echinococcosis: A review with special focus on epidemiology.Frontiers in veterinary science · 2022Review
- Prevalence of Cystic Echinococcosis Genotypes in Iranian Animals: A Systematic Review and Meta-Analysis.Journal of parasitology research · 2022Review
- In vitro evaluation of albendazole-loaded nanostructured lipid carriers on Echinococcus granulosus microcysts and their prophylactic efficacy on experimental secondary hydatidosis.Parasitology research · 2021Article
- Echinococcoses in Iran, Turkey, and Pakistan: Old Diseases in the New Millennium.Clinical microbiology reviews · 2021Article
- Antiparasitic effects ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2020Article
- Genetic characterization ofParasitology · 2019Article
- Prevalence and Molecular Characterization of Echinococcus granulosus Sensu Stricto in Northern Xinjiang, China.The Korean journal of parasitology · 2019Article
- Article
- In vitro and in vivo effects of chitosan-praziquantel and chitosan-albendazole nanoparticles on Echinococcus granulosus Metacestodes.Parasitology research · 2018Article
- Article
- Cystic echinococcosis in Poland: genetic variability and the first record of Echinococcus granulosus sensu stricto (G1 genotype) in the country.Parasitology research · 2017Article
- Dogs' Gastrointestinal Parasites and their Association with Public Health in Iran.Journal of veterinary research · 2017Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cystic echinococcosis (CE), caused by larval stages of the tapeworm Echinococcus granulosus, is one of the most important zoonoses distributed worldwide. Genotype analysis of the parasite isolates from various hosts is required to better understand the host specificity and transmission routes. The aim of this study was to identify the genotypes of E. granulosus isolated from humans and domestic animals from northwest of Iran (Zanjan Province) using the mitochondrial cox1 gene sequence. A total of 86 hydatid cysts including 49 sheep and 28 cattle isolates from the slaughterhouse and nine human isolates from surgical wards of local hospitals were collected. The isolates were subjected to DNA extraction, PCR amplification, and sequence. Eighty-two (95.35 %) isolates, including 47 sheep, 26 cattle, and all nine human isolates, were determined as G1 genotype, and the remaining four (4.65 %), including two sheep and two cattle isolates, were identified as G3 genotype. From the cox1 sequence data, 13 different haplotypes (10 G1s and three G3s) were detected and named as EGH1-EGH13 (GenBank accession numbers, KP859559-KP859571). EGH1 was the major variant among the haplotypes, and it was identified in 46 (53.49 %) isolates (31 sheep, 14 cattle, and one human). Alignment of the partial cox1 sequences showed 12 point mutations including seven (58.3 %) synonymous and five (41.7 %) non-synonymous substitutions. Based on the results, G1 was the major genotype of E. granulosus in northwest of Iran affecting sheep, cattle, and humans. In addition, a minor group of G3 genotype was found to be circulating in this region.
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