Evidence map›Paper›PMID 26280085›Full record

ArticleDigestive diseases and sciences2016

Gastric Electrical Stimulation and Sacral Electrical Stimulation: A Long-Term Follow-Up Study of Dual-Device Treatment.

Anubhav Agrawal, Sean Lamar Francis, Nicolette Elizabeth Deveneau, Shaily Jain, Christopher Abrasley, Jason Trippe McNeese, Shivangi T Kothari, Christopher J Lahr, Thomas L Abell

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Digestive diseases and sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Robotic Setup Promises Consistent Effects of Multilocular Gastrointestinal Electrical Stimulation: First Results of a Porcine Study.European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes · 2020
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Anubhav AgrawalDivision of Female Pelvic Medicine & Reconstructive Surgery, Department of Obstetrics and Gynecology, University of Louisville, Louisville, KY, USA. a0agra05@louisville.edu.
Sean Lamar FrancisDivision of Female Pelvic Medicine & Reconstructive Surgery, Department of Obstetrics and Gynecology, University of Louisville, Louisville, KY, USA. slfran12@louisville.edu.
Nicolette Elizabeth DeveneauDivision of Female Pelvic Medicine & Reconstructive Surgery, Department of Obstetrics and Gynecology, University of Louisville, Louisville, KY, USA. nicolette.deveneau@louisville.edu.
Shaily JainSt. Francis Women's Health Center, Federal Way, WA, USA. sjain@digestivehlth.com.
Christopher AbrasleyWhite-Wilson Medical Center, Fort Walton Beach, FL, USA. cabrasle@white-wilson.com.
Jason Trippe McNeeseGI Associates, Jackson, MS, USA. trippe.mcneese@gastrodocs.com.
Shivangi T KothariUniversity of Rochester Medical Center and Strong Memorial Hospital, Rochester, NY, USA. shivangi_kothari@urmc.rochester.edu.
Christopher J LahrUniversity of Mississippi, Jackson, MS, USA. clahr@umc.edu.
Thomas L AbellDivision of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Louisville, 550 S. Jackson Street, ACB A3L15, Louisville, KY, 40202, USA. thomas.abell@louisville.edu.
University of Louisville · USStrong Memorial Hospital · USUniversity of Mississippi · US

Funding

U of L Clinical Center to Investigate the Pathogenesis, Etiology, and Treatment of Gastroparesis through the NIDDK Gastroparesis ConsortiumU01DK074007 · NIDDK · UNIVERSITY OF MISSISSIPPI MED CTR · PI Thomas Lyman Abell · 2006 to 2026
$7.0M
NIDDK NIH HHS U01 DK074007
6 · The paper itself

Abstract

aimsThe objective of this study was to investigate sacral electrical stimulation (SES) and gastric electrical stimulation (GES) by comparing upper and lower gastrointestinal (GI) and genitourinary (GU) symptoms and quality of life, before treatment and in the long term after treatment. We hypothesized that dual-device treatment would greatly improve upper and lower gastrointestinal and genitourinary symptoms, as well as quality of life.

methodsFifty-four patients who underwent dual-device treatment (GES and SES) were enrolled in this study. Patients who had surpassed 24 months since the second-device insertion were included. Patients were evaluated before and after both devices were implanted and given a symptom questionnaire regarding their upper GI, lower GI, and GU symptoms and their quality of life.

resultsWith combined treatment, a statistically significant improvement was seen in upper GI, lower GI, and GU symptoms and quality of life. However, fecal incontinence and fecal urgency improvements did not reach statistical significance, likely due to the small sample size.

conclusionThe implantation of two stimulators appears to be safe and effective to improve patients' quality of life for those with upper GI symptoms, bowel problems, and bladder dysfunction.

Indexed as

Electrodes, ImplantedAdultDefecationElectric Stimulation TherapyEquipment DesignFecal IncontinenceFemaleFollow-Up StudiesGastric EmptyingGastroparesisHumansIntestinesLumbosacral PlexusMaleQuality of LifeRecovery of FunctionEnterra®GastroparesisIncontinenceInterstim®Neurostimulator

Identifiers

PMID26280085
PMCPMC5098804
OpenAlexW2237213220

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.