Evidence map›Paper›PMID 26279983›Full record

ReviewWorld journal of virology2015

Non-AIDS definings malignancies among human immunodeficiency virus-positive subjects: Epidemiology and outcome after two decades of HAART era.

Pierluigi Brugnaro, Erika Morelli, Francesca Cattelan, Andrea Petrucci, Sandro Panese, Franklyn Eseme, Francesca Cavinato, Andrea Barelli, Enzo Raise

Abstract readReview
In one paragraph

Review in World journal of virology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. HIV and neoplasms: What do we know so far?Einstein (Sao Paulo, Brazil) · 2023
    Pooled it
  2. Article
  3. Differences in Cognition and Smoking Abstinence Rates Among People With and Without HIV Who Smoke.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Observational
  4. Article
  5. Article
  6. Article
  7. CD4Open life sciences · 2023
    Article
  8. Review
  9. Article
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  12. Article
  13. Review
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  15. Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pierluigi BrugnaroPierluigi Brugnaro, Erika Morelli, Francesca Cattelan, Andrea Petrucci, Sandro Panese, Franklyn Eseme, Francesca Cavinato, Andrea Barelli, Enzo Raise, Infectious Diseases Department, Civil Hospital "SS.Giovanni e Paolo", 6776-30122 Venice, Italy.
Erika MorelliPierluigi Brugnaro, Erika Morelli, Francesca Cattelan, Andrea Petrucci, Sandro Panese, Franklyn Eseme, Francesca Cavinato, Andrea Barelli, Enzo Raise, Infectious Diseases Department, Civil Hospital "SS.Giovanni e Paolo", 6776-30122 Venice, Italy.
Francesca CattelanPierluigi Brugnaro, Erika Morelli, Francesca Cattelan, Andrea Petrucci, Sandro Panese, Franklyn Eseme, Francesca Cavinato, Andrea Barelli, Enzo Raise, Infectious Diseases Department, Civil Hospital "SS.Giovanni e Paolo", 6776-30122 Venice, Italy.
Andrea PetrucciPierluigi Brugnaro, Erika Morelli, Francesca Cattelan, Andrea Petrucci, Sandro Panese, Franklyn Eseme, Francesca Cavinato, Andrea Barelli, Enzo Raise, Infectious Diseases Department, Civil Hospital "SS.Giovanni e Paolo", 6776-30122 Venice, Italy.
Sandro PanesePierluigi Brugnaro, Erika Morelli, Francesca Cattelan, Andrea Petrucci, Sandro Panese, Franklyn Eseme, Francesca Cavinato, Andrea Barelli, Enzo Raise, Infectious Diseases Department, Civil Hospital "SS.Giovanni e Paolo", 6776-30122 Venice, Italy.
Franklyn EsemePierluigi Brugnaro, Erika Morelli, Francesca Cattelan, Andrea Petrucci, Sandro Panese, Franklyn Eseme, Francesca Cavinato, Andrea Barelli, Enzo Raise, Infectious Diseases Department, Civil Hospital "SS.Giovanni e Paolo", 6776-30122 Venice, Italy.
Francesca CavinatoPierluigi Brugnaro, Erika Morelli, Francesca Cattelan, Andrea Petrucci, Sandro Panese, Franklyn Eseme, Francesca Cavinato, Andrea Barelli, Enzo Raise, Infectious Diseases Department, Civil Hospital "SS.Giovanni e Paolo", 6776-30122 Venice, Italy.
Andrea BarelliPierluigi Brugnaro, Erika Morelli, Francesca Cattelan, Andrea Petrucci, Sandro Panese, Franklyn Eseme, Francesca Cavinato, Andrea Barelli, Enzo Raise, Infectious Diseases Department, Civil Hospital "SS.Giovanni e Paolo", 6776-30122 Venice, Italy.
Enzo RaisePierluigi Brugnaro, Erika Morelli, Francesca Cattelan, Andrea Petrucci, Sandro Panese, Franklyn Eseme, Francesca Cavinato, Andrea Barelli, Enzo Raise, Infectious Diseases Department, Civil Hospital "SS.Giovanni e Paolo", 6776-30122 Venice, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Highly active antiretroviral therapy (HAART) for human immunodeficiency virus (HIV) infection has been widely available in industrialized countries since 1996; its widespread use determined a dramatic decline in acquired immunodeficiency syndrome (AIDS)-related mortality, and consequently, a significant decrease of AIDS-defining cancers. However the increased mean age of HIV-infected patients, prolonged exposure to environmental and lifestyle cancer risk factors, and coinfection with oncogenic viruses contributed to the emergence of other malignancies that are considered non-AIDS-defining cancers (NADCs) as a relevant fraction of morbidity and mortality among HIV-infected people twenty years after HAART introduction. The role of immunosuppression in the pathogenesis of NADCs is not well defined, and future researches should investigate the etiology of NADCs. In the last years there is a growing evidence that intensive chemotherapy regimens and radiotherapy could be safely administrated to HIV-positive patients while continuing HAART. This requires a multidisciplinary approach and a close co-operation of oncologists and HIV-physicians in order to best manage compliance of patients to treatment and to face drug-related side effects. Here we review the main epidemiological features, risk factors and clinical behavior of the more common NADCs, such as lung cancer, hepatocellular carcinoma, colorectal cancer and anal cancer, Hodgkin's lymphoma and some cutaneous malignancies, focusing also on the current therapeutic approaches and preventive screening strategies.

Indexed as

Highly active antiretroviral therapyHuman immunodeficiency virus infectionMalignancyNon-acquired immunodeficiency syndrome-defining cancers

Identifiers

PMID26279983
PMCPMC4534813

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.