ArticleUnited European gastroenterology journal2015
Systematic review and meta-analysis: Efficacy and safety of POEM for achalasia.
Article in United European gastroenterology journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02572193 (To Assess the Feasibility of Same Day Discharge Following a POEM Procedure), which is not on this map. Cited by 31 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
To Assess the Feasibility of Same Day Discharge Following a POEM Procedure
Who cites it
31 citing papers in PubMed, 5 syntheses or guidelines pooled it, 102 citations in OpenAlex.
- Pneumatic balloon dilatation versus laparoscopic Heller myotomy for achalasia: a failed attempt at meta-analysis.Surgical endoscopy · 2021Pooled it
- Quality of Life Following Peroral Endoscopic Myotomy for Esophageal Achalasia: A Systematic Review and Meta-Analysis.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2020Pooled it
- The 2 years' long-term efficacy and safety of peroral endoscopic myotomy for the treatment of achalasia: a systematic review.Journal of cardiothoracic surgery · 2019Pooled it
- Safety and efficacy of POEM for treatment of achalasia: a systematic review of the literature.Surgical endoscopy · 2017Pooled it
- Is POEM the Answer for Management of Spastic Esophageal Disorders? A Systematic Review and Meta-Analysis.Digestive diseases and sciences · 2017Pooled it
- Endoscopy versus radiology in post-procedural monitoring after peroral endoscopic myotomy (POEM).Surgical endoscopy · 2018Trial
- Efficacy of peroral endoscopic myotomy for the treatment of functional esophagogastric junction outflow obstruction.iGIE : innovation, investigation and insights · 2023Article
- Clinical Outcomes and Complications for Achalasia Patients Admitted After Per-Oral Endoscopic Myotomy.Gastroenterology research · 2023Article
- Third-space endoscopy: the final frontier.Gastroenterology report · 2023Review
- Changes in Distensibility Index During an Incremental POEM Myotomy.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022Article
- Safety and Efficacy of Peroral Endoscopic Shorter Myotomy versus Longer Myotomy for Patients with Achalasia: A Systematic Review and Meta-analysis.Gastroenterology research and practice · 2022Review
- Development of quality indicators for the diagnosis and management of achalasia.Neurogastroenterology and motility · 2021Article
- Delayed Pneumoperitoneum After Peroral Endoscopic Myotomy.ACG case reports journal · 2021Article
- Advances and caveats in modern achalasia management.Therapeutic advances in chronic disease · 2021Review
- Determining the Safety and Effectiveness of Electrocautery Enhanced Scissors for Peroral Endoscopic Myotomy (with Video).Clinical endoscopy · 2020Article
- Long-term outcomes of per-oral endoscopic myotomy in achalasia patients with a minimum follow-up of 4 years: a multicenter study.Endoscopy international open · 2020Article
- Peroral endoscopic myotomy (POEM): a comparative study between Chagasic and idiopathic achalasia.Endoscopy international open · 2020Article
- Esophageal POEM: the new standard of care.Translational gastroenterology and hepatology · 2020Review
- Peroral Endoscopic Myotomy as a Novel Treatment for Achalasia: Patient Selection and Perspectives.Clinical and experimental gastroenterology · 2020Review
- Esophageal Dysphagia in the Elderly.Current treatment options in gastroenterology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeroral endoscopic esophageal myotomy (POEM) represents a less invasive alternative, as compared with conventional laparoscopic Heller myotomy for treating achalasia patients. In the last years, a number of prospective and retrospective experiences with POEM use for achalasia have been published.
methodsRelevant publications in which patients affected by achalasia underwent POEM treatment were identified by PubMed databases for the period 2010 - 2013. From each study, we extracted the number and type of major complications (defined as those requiring any additional medical or surgical intervention). Data were pooled, using random-effects models. Heterogeneity among studies was assessed by using Cochran's Q and the I (2) statistic.
resultsWe found 16 studies that provided data on 551 patients. The median surveillance period was 6 months (range: 3-12). The median of mean POEM duration was 156 minutes (range: 42-112). Median myotomy length was 10 cm (range: 6-14). Technical and clinical success were reported in 97% (95% CI: 94-98%) and 93% (407/428; 95% CI: 90-95%). No heterogeneity (I (2 )= 0%) or publication bias was present in both estimates. When limiting the analysis only to adverse events that require medical or surgical interventions, major adverse events occurred in 14% (95% CI: 11-17%); however, only one patient needed post-POEM surgery (0.2%; 95% CI: 0-0.5%).
conclusionsPOEM appeared to be a highly feasible and effective endoscopic treatment for achalasia. Despite POEM being apparently associated with relatively high morbidity, most patients are successfully managed conservatively, so that POEM appears as a very safe procedure; however, POEM should only be performed in centers able to treat POEM complications, such as pneumothorax or pneumoperitoneum.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.