Evidence map›Paper›PMID 26279661›Full record

ArticleInterventional neurology2015

Ipsilateral Infarct in Newly Diagnosed Cervical Internal Carotid Artery Atherosclerotic Occlusion.

Diogo C Haussen, David Z Rose, Doniel Drazin, Scott D Newsome, Hannah Gardener, Randall C Edgell, Alan Boulos, Gary Bernardini, Tatjana Rundek, Dileep R Yavagal

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Interventional neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Diogo C HaussenDepartment of Neurology, Neurosurgery and Radiology, Emory University School of Medicine, Atlanta, Ga., USA.
David Z RoseDepartment of Neurology, University of South Florida, Tampa, Fla., USA.
Doniel DrazinDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, Calif., USA.
Scott D NewsomeDepartment of Neurology, Johns Hopkins School of Medicine, Baltimore, Md., USA.
Hannah GardenerDepartment of Neurology, University of Miami Miller School of Medicine, Miami, Fla., USA.
Randall C EdgellDepartment of Neurology and Psychiatry, St. Louis University, St. Louis, Mo., USA.
Alan BoulosDepartment of Neurosurgery, Albany Medical Center, Albany, N.Y., USA.
Gary BernardiniDepartment of Neurology, Albany Medical Center, Albany, N.Y., USA.
Tatjana RundekDepartment of Neurology, University of Miami Miller School of Medicine, Miami, Fla., USA.
Dileep R YavagalDepartment of Neurology, University of Miami Miller School of Medicine, Miami, Fla., USA.
University of Miami · USAlbany Medical Center Hospital · USCedars-Sinai Medical Center · USEmory University · USJohns Hopkins University · USUniversity of Missouri–St. Louis · USUniversity of South Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aimed to determine factors associated with recent infarct (RI) in patients with newly identified atherosclerotic cervical internal carotid artery occlusion (CICAO).

methodsThis was a retrospective review of consecutive patients who underwent cervical CT angiography from 2002 to 2006 at a single tertiary center. RI was defined by positive diffusion-weighted imaging/apparent diffusion coefficient magnetic resonance imaging (MRI) in the correspondent CICAO territory. Subjects were dichotomized into those with a RI versus patients with no RI (No-RI).

resultsOf 2,459 patients with cervical CT angiograms in the study period, 108 (4.4%) had complete medical records and brain MRI and were included. The mean age was 64 ± 13 years, 58% were men, and 62 (57%) had a RI. The demographics of the RI and No-RI patients were comparable, with the exception that those with RI had a lower frequency of coronary artery disease (CAD, 13 vs. 54%; p < 0.01) and dyslipidemia (38 vs. 69%; p < 0.01). The use of antiplatelets was not statistically different between the groups (56 vs. 71%; p = 0.1). Subjects with RI were less likely on statins (21 vs. 56%; p < 0.01) and antihypertensives (9 vs. 71%; p < 0.01). Multivariate regression revealed that CAD, the use of statins, and the use of antihypertensives were associated with No-RI CICAO presentation.

conclusionThe use of statins and antihypertensives is associated with a decreased risk of RI atherosclerotic CICAO.

Indexed as

Antihypertensive agentsCarotid artery diseasesHydroxymethylglutaryl-CoA reductase inhibitorsRisk factorsStroke

Identifiers

PMID26279661
PMCPMC4521196
OpenAlexW2216054622

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.