ArticleCurrent directions in psychological science2015
Brain-Body Pathways Linking Psychological Stress and Physical Health.
Article in Current directions in psychological science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06263452 (Beta-Blocker Influences on Inflammatory and Neural Responses to Stress), which is not on this map. Cited by 129 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Beta-Blocker Influences on Inflammatory and Neural Responses to Stress
Who cites it
129 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- A systematic review of co-ethnic exposure and cardiometabolic outcomes in racial and ethnic minoritized populations.Public health reviews · 2026Pooled it
- Exercise training improves blood pressure reactivity to stress: a systematic review and meta-analysis.Scientific reports · 2023Pooled it
- Meta-Analysis on Nicotine's Modulation of HIV-Associated Dementia.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2022Pooled it
- A single session of exercise reduces blood pressure reactivity to stress: a systematic review and meta-analysis.Scientific reports · 2022Pooled it
- Functional neuroanatomy of peripheral inflammatory physiology: A meta-analysis of human neuroimaging studies.Neuroscience and biobehavioral reviews · 2018Pooled it
- Sociodemographic disparities in corticolimbic structures.PloS one · 2019Trial
- Early life adversity diminishes the cortisol response to opioid blockade in women: Studies from the Family Health Patterns project.PloS one · 2018Trial
- A prefrontal cortex-hypothalamus circuit for heart rate control in non-human primates.bioRxiv : the preprint server for biology · 2026Article
- Article
- Ultrasoft, adhesive, pH-tunable hydrogel based on in situ functionalized laser-induced graphene for through-hair concurrent biosensing.Science advances · 2026Article
- From Molecules to Meaning: Integrating Neuropeptides, Sociostasis, and Hormesis in the Brain-Heart Axis.Current issues in molecular biology · 2026Review
- Distinct Subdivisions of the Cingulo-Insular Region and Their Role in Modulating the Cardiac Sympathetic-Parasympathetic Balance.Circulation. Arrhythmia and electrophysiology · 2026Observational
- Potential Effects of Music on Non-Motor Symptoms in Parkinson's Disease: Translating Mechanisms to Therapy.Neurology international · 2026Review
- Neural Control of Autonomic Arousal During Threat Anticipation Revealed by High-Resolution Cardiac Contractility.bioRxiv : the preprint server for biology · 2026Article
- Disturbed Functional Connectivity Between Anterior Default Mode and Sensory Processing Regions Is Linked to Peripheral Inflammatory Markers and Psychopathology in Schizophrenia.Schizophrenia bulletin · 2026Article
- Central autonomic network dysfunction in Stroke-Heart Syndrome: mechanistic roles of the insula and limbic system.Frontiers in neuroscience · 2026Review
- Social and physiological stress elicit divergent psycho-physiological dynamics and motor cortex activation.Frontiers in psychology · 2026Article
- The intrinsic reason why the term "central sensitization" should be refined, by introducing the terms "spinal sensitization", "pain-related brain network sensitization", and "psychosocial-related sensitization".Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Neuroimmune Interactions in Stress and Depression: Exploring the Molecular and Cellular Mechanisms within the Neuroinflammation-depression Nexus.Current medicinal chemistry · 2026Review
- Review
69 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Psychological stress is thought to arise from appraisal processes that ascribe threat-related meaning to experiences that tax or exceed our coping ability. Neuroimaging research indicates that these appraisal processes originate in brain systems that also control physiological stress reactions in the body. Separate lines of research in health psychology and behavioral medicine indicate that these physiological stress reactions confer risk for physical disease. Accordingly, integrative research that cuts across historically separated disciplines may help to define the brain-body pathways linking psychological stress to physical health. We describe recent studies aimed at this goal, focusing on studies of the brain bases of stressor-evoked cardiovascular system reactions and heart disease risk. We also outline an interpretive framework for these studies, as well as needs for next-generation models and metrics to better understand how the brain encodes and embodies stress in relation to health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.